(Q24296913)

NAD-retinol dehydrogenase activity

GOA release 2020-03-11

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GOA release 2020-03-11

author

Gregg Duester

4

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author name string

Chu-Fang Chou

1

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Ching-Long Lai

2

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Yen-Chun Chang

3

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Shih-Jiun Yin

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

12 July 2002

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published in

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volume

277

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issue

28

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page(s)

25209-16

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cites work

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cDNA sequence and catalytic properties of a chick embryo alcohol dehydrogenase that oxidizes retinol and 3beta,5alpha-hydroxysteroids

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Regulation of the mammalian alcohol dehydrogenase genes

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Organization of six functional mouse alcohol dehydrogenase genes on two overlapping bacterial artificial chromosomes

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Involvement of alcohol dehydrogenase, short-chain dehydrogenase/reductase, aldehyde dehydrogenase, and cytochrome P450 in the control of retinoid signaling by activation of retinoic acid synthesis

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Catalytic efficiency of human alcohol dehydrogenases for retinol oxidation and retinal reduction.

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Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase. Active-site amino acid sequence explains substrate specificity compared with liver isozymes

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Terminal-group oxidation of retinol by mouse epidermis. Inhibition in vitro and in vivo

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Human stomach alcohol and aldehyde dehydrogenases: comparison of expression pattern and activities in alimentary tract.

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Regional restriction of alcohol/retinol dehydrogenases along the mouse gastrointestinal epithelium

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Alcohol dehydrogenase in human tissues: localisation of transcripts coding for five classes of the enzyme.

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Alcohol dehydrogenase of human and rat blood vessels. Role in ethanol metabolism.

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Class IV alcohol/retinol dehydrogenase localization in epidermal basal layer: potential site of retinoic acid synthesis during skin development

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Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis

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Localization of class I and class IV alcohol dehydrogenases in mouse testis and epididymis: potential retinol dehydrogenases for endogenous retinoic acid synthesis

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Retinoic acid synthesis in mouse embryos during gastrulation and craniofacial development linked to class IV alcohol dehydrogenase gene expression

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A hypothetical mechanism for fetal alcohol syndrome involving ethanol inhibition of retinoic acid synthesis at the alcohol dehydrogenase step

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Retinoids, omega-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H2-receptor antagonists as pharmacological inhibitors, of human class IV alcohol dehydrogenase

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ADH4-lacZ transgenic mouse reveals alcohol dehydrogenase localization in embryonic midbrain/hindbrain, otic vesicles, and mesencephalic, trigeminal, facial, and olfactory neural crest

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X-ray structure of human class IV sigmasigma alcohol dehydrogenase. Structural basis for substrate specificity

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Molecular basis for differential substrate specificity in class IV alcohol dehydrogenases: a conserved function in retinoid metabolism but not in ethanol oxidation

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Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Some observations on the preparation and properties of dihydronicotinamide-adenine dinucleotide

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Human liver .pi.-Alcohol dehydrogenase: kinetic and molecular properties

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Kinetic mechanism for the major isoenzyme of horse liver alcohol dehydrogenase.

21 January 2018

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Rate constants for a mechanism including intermediates in the interconversion of ternary complexes by horse liver alcohol dehydrogenase

21 January 2018

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Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions

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Mechanistic deductions from isotope effects in multireactant enzyme mechanisms.

21 January 2018

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Molecular docking studies on interaction of diverse retinol structures with human alcohol dehydrogenases predict a broad role in retinoid ligand synthesis

21 January 2018

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Mouse alcohol dehydrogenase 4: kinetic mechanism, substrate specificity and simulation of effects of ethanol on retinoid metabolism

21 January 2018

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Initiation of retinoid signaling in primitive streak mouse embryos: spatiotemporal expression patterns of receptors and metabolic enzymes for ligand synthesis

21 January 2018

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7 January 2021

Impaired retinol utilization in Adh4 alcohol dehydrogenase mutant mice

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7 January 2021

Physiological substrates for rat alcohol dehydrogenase classes: aldehydes of lipid peroxidation, omega-hydroxyfatty acids, and retinoids

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7 January 2021

Identification of endogenous retinoids, enzymes, binding proteins, and receptors during early postimplantation development in mouse: important role of retinal dehydrogenase type 2 in synthesis of all-trans-retinoic acid

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7 January 2021

The catalytic specificity of liver alcohol dehydrogenase: vitamin A alcohol and vitamin A aldehyde activities

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7 January 2021

Expression, activities, and kinetic mechanism of human stomach alcohol dehydrogenase. Inference for first-pass metabolism of ethanol in mammals

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7 January 2021

The equilibrium between vitamin A alcohol and aldehyde in the presence of alcohol dehydrogenase

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7 January 2021

Excitation transfer in complexes of horse liver alcohol dehydrogenase

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7 January 2021

6 Statistical analysis of enzyme kinetic data

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7 January 2021

Fluorescence lifetime and anisotropy studies with liver alcohol dehydrogenase and its complexes

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7 January 2021

Fluorescence quenching of liver alcohol dehydrogenase by acrylamide

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7 January 2021

Solute perturbation of protein fluorescence. Quenching of the tryptophyl fluorescence of model compounds and of lysozyme by iodide ion

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7 January 2021

PRODUCT INHIBITION STUDIES ON YEAST AND LIVER ALCOHOL DEHYDROGENASES

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7 January 2021

Contribution to first-pass metabolism of ethanol and inhibition by ethanol for retinol oxidation in human alcohol dehydrogenase family--implications for etiology of fetal alcohol syndrome and alcohol-related diseases

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7 January 2021

Structural and enzymatic properties of a gastric NADP(H)- dependent and retinal-active alcohol dehydrogenase

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7 January 2021

Horse liver alcohol dehydrogenase. On the primary structures of the isoenzymes

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7 January 2021

Identifiers

DOI

10.1074/JBC.M201947200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

11997393

1 reference

Consolidated OpenCitations Corpus – April 2017