(Q24297189)

English

Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene

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scholarly article

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Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene (English)

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Prospero homeobox 1

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GOA release 2020-03-11

Nuclear receptor subfamily 5 group A member 2

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GOA release 2020-03-11

LBD domain binding

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GOA release 2020-03-11

author name string

Jun Qin

1

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Da-Ming Gao

2

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Quan-Feng Jiang

3

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Qing Zhou

4

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Yu-Ying Kong

5

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Yuan Wang

6

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You-Hua Xie

7

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language of work or name

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publication date

October 2004

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Molecular Endocrinology

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18

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10

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2424-39

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Regulation of the human SIX3 gene promoter.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Prox 1, a prospero-related homeobox gene expressed during mouse development

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the genomic structure and tissue-specific promoter of the human nuclear receptor NR5A2 (hB1F) gene

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of steroidogenic factor 1 and Wilms' tumour 1 during early human gonadal development and sex determination.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclear receptor fetoprotein transcription factor is coexpressed with its target gene HNF-3beta in the developing murine liver, intestine and pancreas.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Coactivator and corepressor complexes in nuclear receptor function

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Bonus, a Drosophila homolog of TIF1 proteins, interacts with nuclear receptors and can inhibit betaFTZ-F1-dependent transcription

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for ligand-independent activation of the orphan nuclear receptor LRH-1

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

On the mechanism of bile acid inhibition of rat sterol 12α-hydroxylase gene (CYP8B1) transcription: roles of α-fetoprotein transcription factor and hepatocyte nuclear factor 4α

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Redundant pathways for negative feedback regulation of bile acid production

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Prox1 function is crucial for mouse lens-fibre elongation

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of sterol 12alpha-hydroxylase alters bile acid pool composition in primary rat hepatocytes and in vivo

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

A contingent replication assay for the detection of protein-protein interactions in animal cells

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Prospero is a panneural transcription factor that modulates homeodomain protein activity.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of a novel human hepatocyte transcription factor, hB1F, which binds and activates enhancer II of hepatitis B virus

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the promoter of the orphan receptor SHP by orphan receptors that bind DNA as monomers

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of human MBF1 as a transcriptional coactivator

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

A zebrafish ftz-F1 (Fushi tarazu factor 1) homologue requires multiple subdomains in the D and E regions for its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Alpha 1-fetoprotein transcription factor is required for the expression of sterol 12alpha -hydroxylase, the specific enzyme for cholic acid synthesis. Potential role in the bile acid-mediated regulation of gene transcription

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The mouse fetoprotein transcription factor (FTF) gene promoter is regulated by three GATA elements with tandem E box and Nkx motifs, and FTF in turn activates the Hnf3beta, Hnf4alpha, and Hnf1alpha gene promoters

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced expression of the human multidrug resistance protein 3 by bile salt in human enterocytes. A transcriptional control of a plausible bile acid transporter

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Ptx1 regulates SF-1 activity by an interaction that mimics the role of the ligand-binding domain

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Liver receptor homolog 1 controls the expression of the scavenger receptor class B type I.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Antagonistic action of Six3 and Prox1 at the gamma-crystallin promoter

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure and specificity of nuclear receptor-coactivator interactions

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Mediators of activation of fushi tarazu gene transcription by BmFTZ-F1

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Prox1 is a novel coregulator of Ff1b and is involved in the embryonic development of the zebra fish interrenal primordium

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of steroidogenic factor-1 and FTF/LRH-1 in the rodent ovary

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1.

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

The DEAD box protein DP103 is a regulator of steroidogenic factor-1

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism

1 reference

https://api.crossref.org/works/10.1210%2FME.2004-0009

7 January 2021

based on heuristic

inferred from DOI database lookup

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