(Q24297583)

WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity

GOA release 2020-03-11

author

László Patthy

series ordinal

3

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author name string

György Szláma

series ordinal

1

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Mária Trexler

series ordinal

2

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language of work or name

English

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publication date

August 2013

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published in

FEBS Journal

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volume

280

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page(s)

3822-39

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issue

16

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

A new model for growth factor activation: type II receptors compete with the prodomain for BMP-7

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Regulation of myostatin activity and muscle growth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

A human protein containing multiple types of protease-inhibitory modules

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Double muscling in cattle due to mutations in the myostatin gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Latent TGF-β structure and activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Genetic analysis of the role of proteolysis in the activation of latent myostatin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Ubiquitous Gasp1 overexpression in mice leads mainly to a hypermuscular phenotype.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Promiscuity and specificity in BMP receptor activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Biological functions of the WAP domain-containing multidomain proteins WFIKKN1 and WFIKKN2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Prodomains of transforming growth factor beta (TGFbeta) superfamily members specify different functions: extracellular matrix interactions and growth factor bioavailability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Administration of a mutated myostatin propeptide to neonatal mice significantly enhances skeletal muscle growth.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Myostatin: a therapeutic target for skeletal muscle wasting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Induction of cachexia in mice by systemically administered myostatin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Distinct expression pattern of two related human proteins containing multiple types of protease-inhibitory modules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

Myostatin blockage using actRIIB antagonism in mice bearing the Lewis lung carcinoma results in the improvement of muscle wasting and physical performance.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3906830

A deletion in the myostatin gene causes the compact (Cmpt) hypermuscular mutation in mice.

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12377

Functional improvement of dystrophic muscle by myostatin blockade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12377

Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12377

Characterization and identification of the inhibitory domain of GDF-8 propeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12377

Myostatin propeptide-mediated amelioration of dystrophic pathophysiology

21 January 2018

1 reference

12 December 2020

Loss of myostatin attenuates severity of muscular dystrophy in mdx mice

1 reference

12 December 2020

Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice

1 reference

12 December 2020

Antagonism of myostatin enhances muscle regeneration during sarcopenia

1 reference

12 December 2020

Prodomains regulate the synthesis, extracellular localisation and activity of TGF-β superfamily ligands

1 reference

12 December 2020