(Q24297590)

English

Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells

scientific article

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scholarly article

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Vascular endothelial growth factor (VEGF)-D and VEGF-A differentially regulate KDR-mediated signaling and biological function in vascular endothelial cells (English)

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Kinase insert domain receptor

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GOA release 2020-03-11

positive regulation of ERK1 and ERK2 cascade

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GOA release 2020-03-11

Michael R. Duchen

4

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author name string

Haiyan Jia

1

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Azadeh Bagherzadeh

2

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Roy Bicknell

3

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Dan Liu

5

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Ian Zachary

6

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language of work or name

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publication date

20 August 2004

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Journal of Biological Chemistry

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279

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34

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36148-57

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The biology of VEGF and its receptors

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https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Angiogenesis in health and disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

VEGF signalling: integration and multi-tasking in endothelial cell biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular permeability factor (VPF)/vascular endothelial growth factor (VEGF) peceptor-1 down-modulates VPF/VEGF receptor-2-mediated endothelial cell proliferation, but not migration, through phosphatidylinositol 3-kinase-dependent pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

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https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Molecular cloning of a novel vascular endothelial growth factor, VEGF-D

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Identification of a c-fos-induced gene that is related to the platelet-derived growth factor/vascular endothelial growth factor family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Adenovirus encoding vascular endothelial growth factor-D induces tissue-specific vascular patterns in vivo.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

VEGF-D is the strongest angiogenic and lymphangiogenic effector among VEGFs delivered into skeletal muscle via adenoviruses

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

The specificity of receptor binding by vascular endothelial growth factor-d is different in mouse and man

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

The angiogenic switch for vascular endothelial growth factor (VEGF)-A, VEGF-B, VEGF-C, and VEGF-D in the adenoma-carcinoma sequence during colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

Vascular endothelial growth factor-D is an independent prognostic factor in epithelial ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

21 January 2018

ErbB2 overexpression correlates with increased expression of vascular endothelial growth factors A, C, and D in human breast carcinoma

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

Peptides encoded by exon 6 of VEGF inhibit endothelial cell biological responses and angiogenesis induced by VEGF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC-delta and by mobilization of intracellular Ca2+

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

Ion channels and their functional role in vascular endothelium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401538200

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1074/JBC.M401538200

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