(Q24297941)

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JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter

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JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter (English)

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author name string

Yuanyuan Rong

1

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Mei Zhang

2

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Lin Zhang

3

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Xing Li Wang

4

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Ying H Shen

5

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language of work or name

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publication date

5 March 2010

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584

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852-8

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Endothelium: interface between coagulation and inflammation

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Endothelial cell dysfunction and coagulation

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Preparation and properties of bovine factor VIII (antihemophilic factor).

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Anticoagulant properties of bovine plasma protein C following activation by thrombin

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Thrombomodulin.

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Novel functions of thrombomodulin in inflammation

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Expression and function of the endothelial protein C receptor in human neutrophils

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Inflammation and the activated protein C anticoagulant pathway

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Down-regulation of endothelial expression of endothelial cell protein C receptor and thrombomodulin in coronary atherosclerosis

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Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins

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Wall tension is a potent negative regulator of in vivo thrombomodulin expression.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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"Jnking" atherosclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Transcription factor and kinase-mediated signaling in atherosclerosis and vascular injury

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Up-regulation of PTEN (phosphatase and tensin homolog deleted on chromosome ten) mediates p38 MAPK stress signal-induced inhibition of insulin signaling. A cross-talk between stress signaling and insulin signaling in resistin-treated human endotheli

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Activation of the AMPK-FOXO3 pathway reduces fatty acid-induced increase in intracellular reactive oxygen species by upregulating thioredoxin

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Up-regulation of thioredoxin interacting protein (Txnip) by p38 MAPK and FOXO1 contributes to the impaired thioredoxin activity and increased ROS in glucose-treated endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Characterization of the ATF/CREB site and its complex with GCN4.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

21 January 2018

Protein C pathway in sepsis

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Soluble thrombomodulin and coronary heart disease

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Epinephrine--via activation of p38-MAPK--abolishes the effect of aspirin on platelet deposition to collagen

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Paclitaxel enhances thrombin-induced endothelial tissue factor expression via c-Jun terminal NH2 kinase activation.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Celecoxib decreases endothelial tissue factor expression through inhibition of c-Jun terminal NH2 kinase phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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jun-N-terminal kinase regulates thrombin-induced PAI-1 gene expression in proximal tubular epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

21 January 2018

Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

21 January 2018

Prolonged shear stress and KLF2 suppress constitutive proinflammatory transcription through inhibition of ATF2.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Blockade of RAGE–amphoterin signalling suppresses tumour growth and metastases

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

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Thrombomodulin-dependent anticoagulant activity is regulated by vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidized low density lipoprotein reduces thrombomodulin transcription in cultured human endothelial cells through degradation of the lipoprotein in lysosomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

1alpha,25-dihydroxyvitamin D(3) and its potent synthetic analogs downregulate tissue factor and upregulate thrombomodulin expression in monocytic cells, counteracting the effects of tumor necrosis factor and oxidized LDL.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombomodulin gene mutations associated with myocardial infarction.

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Local overexpression of thrombomodulin for in vivo prevention of arterial thrombosis in a rabbit model

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of a mouse model for thrombomodulin deficiency

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombomodulin: an overview and potential implications in vascular disorders

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidized phospholipids in oxidized low-density lipoprotein down-regulate thrombomodulin transcription in vascular endothelial cells through a decrease in the binding of RARbeta-RXRalpha heterodimers and Sp1 and Sp3 to their binding sequences in the

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of endothelial thrombomodulin expression by inflammatory cytokines is mediated by activation of nuclear factor-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Patients with severe sepsis vary markedly in their ability to generate activated protein C

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.01.048

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/J.FEBSLET.2010.01.048

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