(Q24298175)

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Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1

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scholarly article

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Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1 (English)

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1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

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GOA release 2020-03-11

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GOA release 2020-03-11

Alpha-2-macroglobulin

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GOA release 2020-03-11

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GOA release 2020-03-11

calcium-dependent protein binding

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

Thai-Yen Ling

1

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Chun-Lin Chen

2

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Yen-Hua Huang

3

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I-Hua Liu

4

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Shuan Shian Huang

5

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Jung San Huang

6

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language of work or name

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publication date

10 September 2004

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Journal of Biological Chemistry

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279

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37

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38736-48

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Receptors for the TGF-β family

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Expression of a new type high molecular weight receptor (type V receptor) of transforming growth factor beta in normal and transformed cells

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Characterization of the inhibition of DNA synthesis in proliferating mink lung epithelial cells by insulin-like growth factor binding protein-3.

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21 January 2018

Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1

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21 January 2018

LRP: a multifunctional scavenger and signaling receptor

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Lipoprotein receptors in the nervous system

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Diverse roles for the LDL receptor family

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Lipoprotein receptors: new roles for ancient proteins.

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The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors

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21 January 2018

alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons

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21 January 2018

Evidence of functional modulation of the MEKK/JNK/cJun signaling cascade by the low density lipoprotein receptor-related protein (LRP).

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Purification of human plasma α2 macroglobulin and α1 proteinase inhibitor using zinc chelate chromatography

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Identification of the high affinity binding site in transforming growth factor-beta involved in complex formation with alpha 2-macroglobulin. Implications regarding the molecular mechanisms of complex formation between alpha 2-macroglobulin and grow

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Fatty acids modulate transforming growth factor-beta activity and plasma clearance

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TGF-beta signal transduction

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The multiligand alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein (alpha 2MR/LRP). Binding and endocytosis of fluid phase and membrane-associated ligands.

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Receptor-associated protein: a specialized chaperone and antagonist for members of the LDL receptor gene family

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Annexins: from structure to function

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Glycosaminoglycan binding properties of annexin IV, V, and VI.

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67 kDa calcimedin, a new Ca2+-binding protein

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Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts

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Antiarrhythmic agents V--calcium blockers

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Late endocytic compartments are major sites of annexin VI localization in NRK fibroblasts and polarized WIF-B hepatoma cells.

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21 January 2018

Characterization and immunolocalization of rat liver annexin VI.

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Annexin VI-mediated loss of spectrin during coated pit budding is coupled to delivery of LDL to lysosomes

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Calcium uptake via endocytosis with rapid release from acidifying endosomes.

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Suramin enters and accumulates in low pH intracellular compartments of v-sis-transformed NIH 3T3 cells

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Insulin-like growth factor (IGF) binding protein-3 regulation of IGF-I is altered in an acidic extracellular environment

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Expression of annexin VI in A431 carcinoma cells suppresses proliferation: a possible role for annexin VI in cell growth regulation

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Biophysical and molecular properties of annexin-formed channels.

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GTP-induced membrane binding and ion channel activity of annexin VI: is annexin VI a GTP biosensor?

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21 January 2018

The low density lipoprotein receptor-related protein complexes with cell surface heparan sulfate proteoglycans to regulate proteoglycan-mediated lipoprotein catabolism

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The apolipoprotein E-dependent low density lipoprotein cholesteryl ester selective uptake pathway in murine adrenocortical cells involves chondroitin sulfate proteoglycans and an alpha 2-macroglobulin receptor

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Receptor-type protein tyrosine phosphatase zeta as a component of the signaling receptor complex for midkine-dependent survival of embryonic neurons

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LDL receptor-related protein as a component of the midkine receptor

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The relevance of tumour pH to the treatment of malignant disease

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A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology

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pH regulates vascular endothelial growth factor binding to fibronectin: a mechanism for control of extracellular matrix storage and release

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Heteromeric and homomeric transforming growth factor-beta receptors show distinct signaling and endocytic responses in epithelial cells

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TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

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Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

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Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor

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Loss of alpha 2-macroglobulin and epidermal growth factor surface binding induced by phenothiazines and naphthalene sulfonamides

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Thioridazine enhances lysosomal accumulation of epidermal growth factor and toxicity of conjugates of epidermal growth factor with Pseudomonas exotoxin

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Removal of lactoferrin from plasma is mediated by binding to low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor and transport to endosomes

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alpha-Macroglobulins: detection and characterization

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Effect of pH and iron content of transferrin on its binding to reticulocyte receptors

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Characterization of receptors for alpha 2-macroglobulin-trypsin complex in rat hepatocytes

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Human tumour pH changes following hyperthermia and radiation therapy

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A practical guide to the preparation of Ca2+ buffers

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Function of the type V transforming growth factor beta receptor in transforming growth factor beta-induced growth inhibition of mink lung epithelial cells

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The type V transforming growth factor beta receptor is the putative insulin-like growth factor-binding protein 3 receptor

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Interactions of high affinity insulin-like growth factor-binding proteins with the type V transforming growth factor-beta receptor in mink lung epithelial cells

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Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment

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7 January 2021

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Cell surface heparan sulfate proteoglycans participate in factor VIII catabolism mediated by low density lipoprotein receptor-related protein

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The role of Grp 78 in alpha 2-macroglobulin-induced signal transduction. Evidence from RNA interference that the low density lipoprotein receptor-related protein is associated with, but not necessary for, GRP 78-mediated signal transduction

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Regulation of vascular endothelial growth factor binding and activity by extracellular pH

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Selection of Pseudomonas exotoxin-resistant cells with altered expression of alpha 2MR/LRP

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10.1074/JBC.M310537200

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