(Q24298879)

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Clinical implication and mitotic effect of CD44 cleavage in relation to osteopontin/CD44 interaction and dysregulated cell cycle protein in gastrointestinal stromal tumor

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scholarly article

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Clinical implication and mitotic effect of CD44 cleavage in relation to osteopontin/CD44 interaction and dysregulated cell cycle protein in gastrointestinal stromal tumor (English)

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gastrointestinal stromal tumor

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author name string

Kai-Hsi Hsu

1

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Hung-Wen Tsai

2

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Pin-Wen Lin

3

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Yun-Shang Hsu

4

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Yan-Shen Shan

5

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Pei-Jung Lu

6

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language of work or name

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publication date

August 2010

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Annals of Surgical Oncology

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17

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8

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2199-212

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Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

21 January 2018

The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

21 January 2018

Expression of Bcl-2 in gastrointestinal stromal tumors: correlation with progression-free survival in 81 patients treated with imatinib mesylate

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Significance of CD44 expression in gastrointestinal stromal tumors in relation to disease progression and survival

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

ADAM-17 associated with CD44 cleavage and metastasis in oral squamous cell carcinoma.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor size is a major determinant of recurrence in patients with resectable gastrointestinal stromal tumor

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hypoxic osteocytes recruit human MSCs through an OPN/CD44-mediated pathway.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 is an integral component of mitotic chromosomes.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: markers with potential prognostic implications.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CD44: structure, function, and association with the malignant process.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

G1 cell-cycle control and cancer

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of osteopontin in tumour progression

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Self-renewal and solid tumor stem cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine activation of an osteopontin-CD44-Rac pathway enhances invasion and transformation by H-RasV12.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Diagnosis of gastrointestinal stromal tumors: A consensus approach

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phenotypic characterization of human colorectal cancer stem cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor cells enhance their own CD44 cleavage and motility by generating hyaluronan fragments

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand-induced structural changes of the CD44 hyaluronan-binding domain revealed by NMR

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential activation of ERK and Rac mediates the proliferative and anti-proliferative effects of hyaluronan and CD44.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclins: roles in mitogenic signaling and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic stratification of high-risk gastrointestinal stromal tumors in the era of targeted therapy

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanism and biological significance of CD44 cleavage

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

PDGFRA activating mutations in gastrointestinal stromal tumors.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Receptor-ligand interaction between CD44 and osteopontin (Eta-1)

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Gamma-secretase-dependent proteolysis of CD44 promotes neoplastic transformation of rat fibroblastic cells.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Normal stem cells and cancer stem cells: the niche matters

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Chondroitin sulfate E fragments enhance CD44 cleavage and CD44-dependent motility in tumor cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Senescent stromal-derived osteopontin promotes preneoplastic cell growth

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Biology of gastrointestinal stromal tumors.

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional regulation of the cyclin D1 gene at a glance

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic significance of osteopontin expression in human gastric carcinoma

1 reference

https://api.crossref.org/works/10.1245%2FS10434-010-0927-1

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1245/S10434-010-0927-1

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release_w5ua2hrc3jggbfwrkabhqeze4a

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