(Q24300129)

N-terminal protein amino acid modification

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

Ponniah Selvakumar

1

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Ashakumary Lakshmikuttyamma

2

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Jonathan R Dimmock

3

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Rajendra K Sharma

Biochimica et Biophysica Acta

4

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language of work or name

English

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publication date

April 2006

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published in

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volume

1765

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issue

2

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page(s)

148-54

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cites work

Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model

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7 January 2021

Yeast methionine aminopeptidase type 1 is ribosome-associated and requires its N-terminal zinc finger domain for normal function in vivo.

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7 January 2021

Yeast methionine aminopeptidase I can utilize either Zn2+ or Co2+ as a cofactor: a case of mistaken identity?

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7 January 2021

Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases

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7 January 2021

Evidence that the human homologue of a rat initiation factor-2 associated protein (p67) is a methionine aminopeptidase

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7 January 2021

Induction of apoptosis due to lowering the level of eukaryotic initiation factor 2-associated protein, p67, from mammalian cells by antisense approach

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7 January 2021

Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Evidence that two zinc fingers in the methionine aminopeptidase from Saccharomyces cerevisiae are important for normal growth

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7 January 2021

Novel vascular targeting/disrupting agents: combretastatin A4 phosphate and related compounds

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7 January 2021

Hydroxylamine-stable covalent linkage of myristic acid in G0 alpha, a guanine nucleotide-binding protein of bovine brain

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Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

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7 January 2021

Identification of the NH2-terminal blocking group of calcineurin B as myristic acid

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7 January 2021

Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor

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7 January 2021

Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29.

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7 January 2021

Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents

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7 January 2021

Prospects for therapeutic inhibition of neuroblastoma angiogenesis

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7 January 2021

The C. elegans methionine aminopeptidase 2 analog map-2 is required for germ cell proliferation.

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7 January 2021

Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity

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7 January 2021

Structure and function of the methionine aminopeptidases

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7 January 2021

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7 January 2021

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families

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7 January 2021

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.

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7 January 2021

Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2).

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7 January 2021

Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Characterization of full length and truncated type I human methionine aminopeptidases expressed from Escherichia coli.

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

The methionyl aminopeptidase from Escherichia coli can function as an iron(II) enzyme

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Role of Methionine in the Initiation of Haemoglobin Synthesis

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7 January 2021

Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src

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7 January 2021

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

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7 January 2021

Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470).

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7 January 2021

Methionine aminopeptidases and angiogenesis

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Early and late functions associated with the Golgi apparatus reside in distinct compartments

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Covalently bound myristate in a lymphoma tyrosine protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Dephosphorylation of catalytic subunit of cAMP-dependent protein kinase at Thr-197 by a cellular protein phosphatase and by purified protein phosphatase-2A

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Yeast methionine aminopeptidase I. Alteration of substrate specificity by site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4.

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

The biology and enzymology of protein N-myristoylation

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Dissection of the Golgi complex. II. Density separation of specific Golgi functions in virally infected cells treated with monensin

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

High expression of methionine aminopeptidase type 2 in germinal center B cells and their neoplastic counterparts

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Structure of human methionine aminopeptidase-2 complexed with fumagillin

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Characterization of cDNA clones for the human c-yes gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Genetic and biochemical studies of protein N-myristoylation

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Depletion of methionine aminopeptidase 2 does not alter cell response to fumagillin or bengamides

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

High expression of methionine aminopeptidase 2 in human colorectal adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team

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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Role of aminopeptidase in angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Effect of ionizing irradiation on human esophageal cancer cell lines by cDNA microarray gene expression analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

TNP-470: an angiogenesis inhibitor in clinical development for cancer

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021

Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001

7 January 2021