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Methionine aminopeptidase 2 and cancer
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scholarly article
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title
Methionine aminopeptidase 2 and cancer
(English)
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main subject
Methionyl aminopeptidase 1
1 reference
stated in
GOA release 2020-03-11
N-terminal protein amino acid modification
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stated in
GOA release 2020-03-11
author name string
Ponniah Selvakumar
series ordinal
1
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Ashakumary Lakshmikuttyamma
series ordinal
2
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Jonathan R Dimmock
series ordinal
3
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Rajendra K Sharma
series ordinal
4
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language of work or name
English
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publication date
April 2006
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published in
Biochimica et Biophysica Acta
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volume
1765
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issue
2
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page(s)
148-54
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cites work
Novel inhibitors targeted to methionine aminopeptidase 2 (MetAP2) strongly inhibit the growth of cancers in xenografted nude model
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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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Yeast methionine aminopeptidase type 1 is ribosome-associated and requires its N-terminal zinc finger domain for normal function in vivo.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Yeast methionine aminopeptidase I can utilize either Zn2+ or Co2+ as a cofactor: a case of mistaken identity?
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Evidence that the human homologue of a rat initiation factor-2 associated protein (p67) is a methionine aminopeptidase
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Induction of apoptosis due to lowering the level of eukaryotic initiation factor 2-associated protein, p67, from mammalian cells by antisense approach
1 reference
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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Evidence that two zinc fingers in the methionine aminopeptidase from Saccharomyces cerevisiae are important for normal growth
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Novel vascular targeting/disrupting agents: combretastatin A4 phosphate and related compounds
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
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Hydroxylamine-stable covalent linkage of myristic acid in G0 alpha, a guanine nucleotide-binding protein of bovine brain
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent
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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Identification of the NH2-terminal blocking group of calcineurin B as myristic acid
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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Specific and saturable binding of pp60v-src to plasma membranes: evidence for a myristyl-src receptor
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Expression of methionine aminopeptidase 2, N-myristoyltransferase, and N-myristoyltransferase inhibitor protein 71 in HT29.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Prospects for therapeutic inhibition of neuroblastoma angiogenesis
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https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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The C. elegans methionine aminopeptidase 2 analog map-2 is required for germ cell proliferation.
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Methionine aminopeptidase-2 regulates human mesothelioma cell survival: role of Bcl-2 expression and telomerase activity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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inferred from DOI database lookup
Structure and function of the methionine aminopeptidases
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Myristoylation
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Steady-state kinetic characterization of substrates and metal-ion specificities of the full-length and N-terminally truncated recombinant human methionine aminopeptidases (type 2).
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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A glycosylation site, 60SGTS63, of p67 is required for its ability to regulate the phosphorylation and activity of eukaryotic initiation factor 2alpha.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
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Characterization of full length and truncated type I human methionine aminopeptidases expressed from Escherichia coli.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
The methionyl aminopeptidase from Escherichia coli can function as an iron(II) enzyme
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of Methionine in the Initiation of Haemoglobin Synthesis
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a 32K plasma membrane protein that binds to the myristylated amino-terminal sequence of p60v-src
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
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Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470).
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methionine aminopeptidases and angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
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Early and late functions associated with the Golgi apparatus reside in distinct compartments
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
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inferred from DOI database lookup
n-Tetradecanoyl is the NH2-terminal blocking group of the catalytic subunit of cyclic AMP-dependent protein kinase from bovine cardiac muscle
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Covalently bound myristate in a lymphoma tyrosine protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
yes-related protooncogene, syn, belongs to the protein-tyrosine kinase family
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myristoylated alpha subunits of guanine nucleotide-binding regulatory proteins
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Eukaryotic methionyl aminopeptidases: two classes of cobalt-dependent enzymes
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The antiangiogenic agent TNP-470 requires p53 and p21CIP/WAF for endothelial cell growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dephosphorylation of catalytic subunit of cAMP-dependent protein kinase at Thr-197 by a cellular protein phosphatase and by purified protein phosphatase-2A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Yeast methionine aminopeptidase I. Alteration of substrate specificity by site-directed mutagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methionine aminopeptidase 2 is a new target for the metastasis-associated protein, S100A4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
The biology and enzymology of protein N-myristoylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Dissection of the Golgi complex. II. Density separation of specific Golgi functions in virally infected cells treated with monensin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High expression of methionine aminopeptidase type 2 in germinal center B cells and their neoplastic counterparts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of human methionine aminopeptidase-2 complexed with fumagillin
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of cDNA clones for the human c-yes gene
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic and biochemical studies of protein N-myristoylation
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Depletion of methionine aminopeptidase 2 does not alter cell response to fumagillin or bengamides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High expression of methionine aminopeptidase 2 in human colorectal adenocarcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fumagillin analog in the treatment of Kaposi's sarcoma: a phase I AIDS Clinical Trial Group study. AIDS Clinical Trial Group No. 215 Team
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multi-institutional study of the angiogenesis inhibitor TNP-470 in metastatic renal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of aminopeptidase in angiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of ionizing irradiation on human esophageal cancer cell lines by cDNA microarray gene expression analysis
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
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7 January 2021
based on heuristic
inferred from DOI database lookup
TNP-470: an angiogenesis inhibitor in clinical development for cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fumagillin treatment of hepatocellular carcinoma in rats: an in vivo study of antiangiogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.BBCAN.2005.11.001
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.BBCAN.2005.11.001
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PubMed publication ID
16386852
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