(Q24300545)

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Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5

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scholarly article

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Evolution of glycoprotein hormone subunit genes in bilateral metazoa: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5 (English)

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Glycoprotein hormone subunit alpha 2

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GOA release 2020-03-11

Glycoprotein hormone alpha 2

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GOA release 2020-03-11

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author name string

Sheau Yu Hsu

1

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Koji Nakabayashi

2

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Alka Bhalla

3

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language of work or name

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publication date

July 2002

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Molecular Endocrinology

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16

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7

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1538-51

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The beta chorionic gonadotropin-beta luteinizing gene cluster maps to human chromosome 19

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Human chromosome 19 contains the neurotrophin-5 gene locus and three related genes that may encode novel acidic neurotrophins

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Receptor-binding regions in human glycoprotein hormones

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Inherited disorders of the gonadotropin hormones

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hCG-receptor binding and transmembrane signaling

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Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein

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The gene lin-3 encodes an inductive signal for vulval development in C. elegans

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Crystal structure of human chorionic gonadotropin

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Solution structure of the alpha-subunit of human chorionic gonadotropin

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A G protein-coupled receptor with low density lipoprotein-binding motifs suggests a role for lipoproteins in G-linked signal transduction

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Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons

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In vivo responses of the primate corpus luteum to luteinizing hormone and chorionic gonadotropin

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Molecular cloning, genomic organization, and developmental regulation of a novel receptor from Drosophila melanogaster structurally related to members of the thyroid-stimulating hormone, follicle-stimulating hormone, luteinizing hormone/choriogonado

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Cystine knot of the gonadotropin alpha subunit is critical for intracellular behavior but not for in vitro biological activity

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Cystine knot mutations affect the folding of the glycoprotein hormone alpha-subunit. Differential secretion and assembly of partially folded intermediates

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Gonadotropin beta subunits determine the rate of assembly and the oligosaccharide processing of hormone dimer in transfected cells

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Cosmid mapping of the human chorionic gonadotropin beta subunit genes by field-inversion gel electrophoresis

1 reference

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Phylogenetic analysis of the vertebrate glycoprotein hormone family including new sequences of sturgeon (Acipenser baeri) beta subunits of the two gonadotropins and the thyroid-stimulating hormone

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Targeted disruption of the pituitary glycoprotein hormone alpha-subunit produces hypogonadal and hypothyroid mice.

1 reference

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Molecular cloning, genomic organization, developmental regulation, and a knock-out mutant of a novel leu-rich repeats-containing G protein-coupled receptor (DLGR-2) from Drosophila melanogaster

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Activation of orphan receptors by the hormone relaxin

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Gonadotrophin and thyrotrophin receptors

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Characterization of two fly LGR (leucine-rich repeat-containing, G protein-coupled receptor) proteins homologous to vertebrate glycoprotein hormone receptors: constitutive activation of wild-type fly LGR1 but not LGR2 in transfected mammalian cells

1 reference

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Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

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Evolution and Classification of Cystine Knot-Containing Hormones and Related Extracellular Signaling Molecules

1 reference

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based on heuristic

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A comprehensive evolutionary analysis based on nucleotide and amino acid sequences of the alpha- and beta-subunits of glycoprotein hormone gene family

1 reference

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based on heuristic

inferred from DOI database lookup

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10.1210/MEND.16.7.0871

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