(Q24300910)

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Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells

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Nodal enhances the activity of FoxO3a and its synergistic interaction with Smads to regulate cyclin G2 transcription in ovarian cancer cells (English)

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G Fu

1

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C Peng

2

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publication date

15 September 2011

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30

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37

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3953-66

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A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B' subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Cyclin G1 and cyclin G2 comprise a new family of cyclins with contrasting tissue-specific and cell cycle-regulated expression

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Control of cyclin G2 mRNA expression by forkhead transcription factors: novel mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Smad transcription factors

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Crystal structure of the human FOXO3a-DBD/DNA complex suggests the effects of post-translational modification

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Role and regulation of nodal/activin receptor-like kinase 7 signaling pathway in the control of ovarian follicular atresia

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Nodal induces apoptosis and inhibits proliferation in human epithelial ovarian cancer cells via activin receptor-like kinase 7

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Activin receptor-like kinase 7 induces apoptosis through up-regulation of Bax and down-regulation of Xiap in normal and malignant ovarian epithelial cell lines

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

Activin receptor-like kinase 7 induces apoptosis of pancreatic beta cells and beta cell lines

1 reference

https://api.crossref.org/works/10.1038/ONC.2011.127

20 April 2017

TGF-beta signaling in tumor suppression and cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

20 April 2017

FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

FOXO transcription factors cooperate with delta EF1 to activate growth suppressive genes in B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

A FoxO-Smad synexpression group in human keratinocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Critical role for FoxO3a-dependent regulation of p21CIP1/WAF1 in response to statin signaling in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Dynamic FoxO transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

FOXO transcription factor-dependent p15(INK4b) and p19(INK4d) expression.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal and Cripto-1: embryonic pattern formation genes involved in mammary gland development and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Cyclin G2 dysregulation in human oral cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Roles of human epidermal growth factor receptor 2, c-jun NH2-terminal kinase, phosphoinositide 3-kinase, and p70 S6 kinase pathways in regulation of cyclin G2 expression in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Regulation of FOXO3a/beta-catenin/GSK-3beta signaling by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Ovarian cancer metastasis: integrating insights from disparate model organisms

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Expression of nodal signalling components in cycling human endometrium and in endometrial cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal Signaling in Vertebrate Development

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal signalling in vertebrate development.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal signaling: developmental roles and regulation.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Estrogen-occupied estrogen receptor represses cyclin G2 gene expression and recruits a repressor complex at the cyclin G2 promoter

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Emerging roles of nodal and Cripto-1: from embryogenesis to breast cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

The pro-domain of the zebrafish Nodal-related protein Cyclops regulates its signaling activities.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Forkhead box-O transcription factor: critical conductors of cancer's fate

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

MicroRNA 376c enhances ovarian cancer cell survival by targeting activin receptor-like kinase 7: implications for chemoresistance

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Regulation of transactivation-independent proapoptotic activity of p53 by FOXO3a

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Nodal and lefty signaling regulates the growth of pancreatic cells

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

21 January 2018

Low expression of Foxo3a is associated with poor prognosis in ovarian cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.127

31 March 2020

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10.1038/ONC.2011.127

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