(Q24304274)

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Differential regulation of ceramide in lipid-rich microdomains (rafts): antagonistic role of palmitoyl:protein thioesterase and neutral sphingomyelinase 2

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scholarly article

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Differential regulation of ceramide in lipid-rich microdomains (rafts): antagonistic role of palmitoyl:protein thioesterase and neutral sphingomyelinase 2 (English)

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Palmitoyl-protein thioesterase 1

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GOA release 2020-03-11

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based on heuristic

inferred from title

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author name string

R Goswami

1

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M Ahmed

2

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J Kilkus

3

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T Han

4

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S A Dawson

5

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G Dawson

6

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language of work or name

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publication date

15 July 2005

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Journal of Neuroscience Research

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81

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2

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208-17

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A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling

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https://api.crossref.org/works/10.1002%2FJNR.20549

21 January 2018

Antisense palmitoyl protein thioesterase 1 (PPT1) treatment inhibits PPT1 activity and increases cell death in LA-N-5 neuroblastoma cells

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis

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7 January 2021

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Ceramide in rafts (detergent-insoluble fraction) mediates cell death in neurotumor cell lines

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7 January 2021

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Regulation of sphingomyelinases in cells of the oligodendrocyte lineage

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7 January 2021

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Regulation of phospholipase D activity in a human oligodendroglioma cell line (HOG).

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7 January 2021

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Does ceramide play a role in neural cell apoptosis?

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Neuronal trafficking of palmitoyl protein thioesterase provides an excellent model to study the effects of different mutations which cause infantile neuronal ceroid lipofuscinocis

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7 January 2021

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A rapid fluorogenic palmitoyl-protein thioesterase assay: pre- and postnatal diagnosis of INCL

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7 January 2021

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Characterization of a cell line derived from a human oligodendroglioma

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7 January 2021

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Apoptosis is associated with an inhibition of aminophospholipid translocase (APTL) in CNS-derived HN2-5 and HOG cells and phosphatidylserine is a recognition molecule in microglial uptake of the apoptotic HN2-5 cells

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Reversible palmitoylation of signaling proteins

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Ceramide in the eukaryotic stress response

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Ceramide and apoptosis

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Regulation of death receptor signaling and apoptosis by ceramide

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7 January 2021

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Myelin glycosphingolipid/cholesterol-enriched microdomains selectively sequester the non-compact myelin proteins CNP and MOG

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Functional rafts in cell membranes

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Organelle-specific initiation of cell death pathways

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Cancer genes and the pathways they control

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Ceramide-mediated clustering is required for CD95-DISC formation

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Palmitoyl protein thioesterase 1 protects against apoptosis mediated by Ras-Akt-caspase pathway in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Phosphoinositide 3-kinase regulates crosstalk between Trk A tyrosine kinase and p75(NTR)-dependent sphingolipid signaling pathways

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7 January 2021

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Acid sphingomyelinase and inhibition by phosphate ion: role of inhibition by phosphatidyl-myo-inositol 3,4,5-triphosphate in oligodendrocyte cell signaling

1 reference

https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Compartmentalized Production of Ceramide at the Cell Surface

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Lysosomal targeting of palmitoyl-protein thioesterase

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

1 reference

https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase

1 reference

https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Flotillin-1/reggie-2 traffics to surface raft domains via a novel golgi-independent pathway. Identification of a novel membrane targeting domain and a role for palmitoylation

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

based on heuristic

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Biochemical properties of mammalian neutral sphingomyelinase 2 and its role in sphingolipid metabolism

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

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https://api.crossref.org/works/10.1002%2FJNR.20549

7 January 2021

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A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

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7 January 2021

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Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-beta-induced JNK activation

1 reference

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7 January 2021

based on heuristic

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Palmitoylation of intracellular signaling proteins: regulation and function

1 reference

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7 January 2021

based on heuristic

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Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis.

1 reference

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7 January 2021

based on heuristic

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Posttranslational protein S-palmitoylation and the compartmentalization of signaling molecules in neurons

1 reference

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7 January 2021

based on heuristic

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10.1002/JNR.20549

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