(Q24305927)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

title

The cystine knot promotes folding and not thermodynamic stability in vascular endothelial growth factor (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990150

vascular endothelial growth factor A

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

author name string

Christoph Heiring

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Rolf Misselwitz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Karin Welfle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

Heinz Welfle

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

language of work or name

English

0 references

publication date

30 August 2002

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

12 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

277

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

issue

45

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

page(s)

43410-43416

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

12 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Roles of individual disulfide bonds in the stability and folding of an omega-conotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Disulfide bonds and the stability of globular proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Folding screening assayed by proteolysis: application to various cystine deletion mutants of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Calculation of protein extinction coefficients from amino acid sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

21 January 2018

Protein stability curves

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Validity of the "two-state" hypothesis for conformational transitions of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Conformational stability and thermodynamics of folding of ribonucleases Sa, Sa2 and Sa3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Two exposed amino acid residues confer thermostability on a cold shock protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Enthalpy-entropy compensation phenomena in water solutions of proteins and small molecules: A ubiquitous properly of water

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Cystine knot mutations affect the folding of the glycoprotein hormone alpha-subunit. Differential secretion and assembly of partially folded intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Crystal structure of the complex between VEGF and a receptor-blocking peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Intracellular folding pathway of the cystine knot-containing glycoprotein hormone alpha-subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Vascular endothelial growth factor: crystal structure and functional mapping of the kinase domain receptor binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Expanding the model: anisotropic displacement parameters in protein structure refinement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

Hyperthermophile protein folding thermodynamics: differential scanning calorimetry and chemical denaturation of Sac7d

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

7 January 2021

Thermodynamics of denaturation of mutants of barnase with disulfide crosslinks

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

7 January 2021

Mechanism of specificity in the Fos-Jun oncoprotein heterodimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

7 January 2021

Variations on ligand-receptor complexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

7 January 2021

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M206438200

7 January 2021

Identifiers

DOI

10.1074/JBC.M206438200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12207021%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

1 reference