(Q24306771)

1

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Laura P Newman

2

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Radhika Desai

3

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Patricia J Keely

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

8 December 2006

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published in

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volume

281

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issue

49

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page(s)

37527-35

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cites work

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Rho GTPases. Integrating integrin signaling

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

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A role for Rac in Tiam1-induced membrane ruffling and invasion

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

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Integrins and GTPases in tumour cell growth, motility and invasion

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A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42

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Cloning and characterization of a novel Cdc42-associated tyrosine kinase, ACK-2, from bovine brain

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Fibronectin matrix regulates activation of RHO and CDC42 GTPases and cell cycle progression

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The tyrosine kinase ACK1 associates with clathrin-coated vesicles through a binding motif shared by arrestin and other adaptors

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Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation

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Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck

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HSH2: a novel SH2 domain-containing adapter protein involved in tyrosine kinase signaling in hematopoietic cells

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SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1

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Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1.

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Stimulation of M3 muscarinic receptors induces phosphorylation of the Cdc42 effector activated Cdc42Hs-associated kinase-1 via a Fyn tyrosine kinase signaling pathway

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Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation

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Stimulation of Ras guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) upon tyrosine phosphorylation by the Cdc42-regulated kinase ACK1

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Melanoma chondroitin sulphate proteoglycan regulates cell spreading through Cdc42, Ack-1 and p130cas

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Modulation of HeLa cells spreading by the non-receptor tyrosine kinase ACK-2.

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Construction of a cell-permeable CDC42 binding fragment of ACK that inhibits v-Ha-Ras transformation

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Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance.

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Requirement of activated Cdc42-associated kinase for survival of v-Ras-transformed mammalian cells

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Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox

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Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1

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Initiating oncogenic event determines gene-expression patterns of human breast cancer models

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Signal transduction by integrins: increased protein tyrosine phosphorylation caused by clustering of beta 1 integrins

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Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

21 January 2018

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CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

21 January 2018

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

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Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and Src

21 January 2018

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Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas

21 January 2018

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Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

21 January 2018

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Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration

21 January 2018

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Signaling networks linking integrins and rho family GTPases.

21 January 2018

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The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor

21 January 2018

1 reference

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AlphaPIX and betaPIX and their role in focal adhesion formation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M604342200

Role of Cdc42 in neurite outgrowth of PC12 cells and cerebellar granule neurons

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604342200