(Q24306834)

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Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence

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Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence (English)

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reactive oxygen species

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based on heuristic

inferred from title

cellular senescence

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based on heuristic

inferred from title

author name string

Hong Seok Kim

1

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Myeong-Cheol Song

2

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In Hae Kwak

3

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Tae Jun Park

4

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In Kyoung Lim

5

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language of work or name

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publication date

26 September 2003

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Journal of Biological Chemistry

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278

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37497-510

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39

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The serial cultivation of human diploid cell strains

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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Multiple Ras functions can contribute to mammalian cell transformation

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Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.

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PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

1 reference

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21 January 2018

Protein phosphatases and the regulation of MAP kinase activity

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Molecular cloning and characterization of a novel dual specificity phosphatase, MKP-5

1 reference

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Separation and Characterization of Two Phosphorylase Phosphatase Inhibitors from Rabbit Skeletal Muscle

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Redox regulation of NF-kappa B activation

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Oxidants as stimulators of signal transduction

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Requirement for generation of H2O2 for platelet-derived growth factor signal transduction

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Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury

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The phosphorylation of eukaryotic initiation factor eIF4E in response to phorbol esters, cell stresses, and cytokines is mediated by distinct MAP kinase pathways

1 reference

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Protein phosphatase 1 is a molecular constraint on learning and memory.

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The use of animal models to study the effects of aging on cognition

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Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1

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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

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Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress.

1 reference

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Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein

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Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster

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EGF receptor-ERK pathway is the major signaling pathway that mediates upregulation of aldose reductase expression under oxidative stress

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Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate

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Peroxisome senescence in human fibroblasts

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Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import

1 reference

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The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

1 reference

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Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

1 reference

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Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase)

1 reference

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Activation of ternary complex factor Elk-1 by MAP kinases

1 reference

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Okadaic acid. Protein phosphatase inhibition and muscle contractile effects

1 reference

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7 January 2021

based on heuristic

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Reconstitution of a Mg‐ATP‐dependent protein phosphatase and its activation through a phosphorylation mechanism

1 reference

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Thiol-mediated redox regulation of neutrophil apoptosis

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Cytoplasmic retention of p-Erk1/2 and nuclear accumulation of actin proteins during cellular senescence in human diploid fibroblasts

1 reference

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1 reference

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Specific and reversible inactivation of protein tyrosine phosphatases by hydrogen peroxide: evidence for a sulfenic acid intermediate and implications for redox regulation

1 reference

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The dual specificity phosphatases M3/6 and MKP-3 are highly selective for inactivation of distinct mitogen-activated protein kinases

1 reference

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Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2

1 reference

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1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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Identifiers

10.1074/JBC.M211739200

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release_qgo7gq47ubebhhysmnosb5m264

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24 November 2022

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mapped directly with Wikidata item

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