(Q24307533)

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Progesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 Reductase

scientific article published on November 16, 2010

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Progesterone receptor membrane component 1 inhibits the activity of drug-metabolizing cytochromes P450 and binds to cytochrome P450 reductase (English)

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Progesterone Receptor Membrane Component 1 Inhibits the Activity of Drug-Metabolizing Cytochromes P450 and Binds to Cytochrome P450 Reductase (English)

1 reference

10.1124/MOL.110.068478

https://api.crossref.org/works/10.1124/MOL.110.068478

27 August 2024

cytochrome P-450 enzyme inhibitors

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

author name string

Elzbieta Szczesna-Skorupa

1

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Byron Kemper

2

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publication date

March 2011

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16 November 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

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https://europepmc.org/articles/pmc3061357?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

http://molpharm.aspetjournals.org/cgi/content/abstract/79/3/340

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081644/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21081644/?tool=EBI

online access status

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://europepmc.org/articles/PMC3061357

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Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://europepmc.org/articles/PMC3061357?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://doi.org/10.1124/mol.110.068478

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21081644

27 August 2024

https://syndication.highwire.org/content/doi/10.1124/mol.110.068478

1 reference

10.1124/MOL.110.068478

https://api.crossref.org/works/10.1124/MOL.110.068478

27 August 2024

Molecular Pharmacology

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79

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3

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340-50

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Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae

1 reference

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19 March 2017

Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor

1 reference

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19 March 2017

Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51.

1 reference

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19 March 2017

Photo-leucine and photo-methionine allow identification of protein-protein interactions in living cells

1 reference

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19 March 2017

The many roles of cytochrome b5

1 reference

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19 March 2017

The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans

1 reference

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19 March 2017

Protein sensors for membrane sterols

1 reference

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7 April 2017

CYP2C8 exists as a dimer in natural membranes

1 reference

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27 September 2017

Progesterone receptor membrane component 1 (Pgrmc1): a heme-1 domain protein that promotes tumorigenesis and is inhibited by a small molecule

1 reference

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27 September 2017

PGRMC1 (progesterone receptor membrane component 1): a targetable protein with multiple functions in steroid signaling, P450 activation and drug binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Genetic variation in human P450 oxidoreductase.

1 reference

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27 September 2017

Alterations in the expression, structure and function of progesterone receptor membrane component-1 (PGRMC1) in premature ovarian failure

1 reference

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27 September 2017

Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Progesterone receptor membrane component 1--many tasks for a versatile protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Influence of protein-protein interactions on the cellular localization of cytochrome P450.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Progesterone receptor membrane component 1: an integrative review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Molecular identification of adrenal inner zone antigen as a heme-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Characterization of the adrenal-specific antigen IZA (inner zone antigen) and its role in the steroidogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Organization of multiple cytochrome P450s with NADPH-cytochrome P450 reductase in membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Localization and topology of ratp28, a member of a novel family of putative steroid-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Mobility of cytochrome P450 in the endoplasmic reticulum membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Isolation and characterization of a novel gene induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rat liver.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Cytochromes P450 expression systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

NH2-terminal substitutions of basic amino acids induce translocation across the microsomal membrane and glycosylation of rabbit cytochrome P450IIC2.

1 reference

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27 September 2017

The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061357

27 September 2017

Domain motion in cytochrome P450 reductase: conformational equilibria revealed by NMR and small-angle x-ray scattering.

1 reference

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30 May 2018

Endoplasmic reticulum retention determinants in the transmembrane and linker domains of cytochrome P450 2C1.

1 reference

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30 May 2018

Identification of the binding site on cytochrome P450 2B4 for cytochrome b5 and cytochrome P450 reductase.

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30 May 2018

The amino-terminal 29 amino acids of cytochrome P450 2C1 are sufficient for retention in the endoplasmic reticulum.

1 reference

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30 May 2018

10 Heterologous expression of mammalian P450 in COS cells

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Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.

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Simultaneous absolute quantification of 11 cytochrome P450 isoforms in human liver microsomes by liquid chromatography tandem mass spectrometry with in silico target peptide selection.

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Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21081644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21081644

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1124/MOL.110.068478

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