(Q24307921)

3

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author name string

Robert J Johnston

1

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Laetitia Comps-Agrar

2

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Xin Yu

4

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Mahrukh Huseni

5

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Yagai Yang

6

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Summer Park

7

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Vincent Javinal

8

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Henry Chiu

9

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Bryan Irving

10

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Dan L Eaton

11

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Jane L Grogan

Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection

12

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language of work or name

English

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publication date

8 December 2014

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published in

Cancer Cell

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volume

26

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issue

6

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page(s)

923-37

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cites work

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7 January 2021

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

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Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR.

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7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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7 January 2021

T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment

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7 January 2021

B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

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7 January 2021

Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

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7 January 2021

Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.

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7 January 2021

Adoptive T cell transfer for cancer immunotherapy in the era of synthetic biology

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Dendritic-cell-based therapeutic cancer vaccines

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7 January 2021

Turning tumors into vaccines: co-opting the innate immune system

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Oncology meets immunology: the cancer-immunity cycle

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7 January 2021

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

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7 January 2021

CD8 T cell defect of TNF-α and IL-2 in DNAM-1 deficient mice delays clearance in vivo of a persistent virus infection

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7 January 2021

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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7 January 2021

Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells

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7 January 2021

Restoring function in exhausted CD8 T cells during chronic viral infection

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7 January 2021

Cancer immunotherapy comes of age

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7 January 2021

Comprehensive molecular characterization of human colon and rectal cancer

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7 January 2021

Comprehensive genomic characterization of squamous cell lung cancers

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7 January 2021

Comprehensive molecular portraits of human breast tumours

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7 January 2021

Integrated genomic characterization of endometrial carcinoma

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7 January 2021

Comprehensive molecular characterization of clear cell renal cell carcinoma

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7 January 2021

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

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7 January 2021

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

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7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

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7 January 2021

Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: application to GPCR oligomerization

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Molecular mechanisms of T cell co-stimulation and co-inhibition

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Nivolumab plus ipilimumab in advanced melanoma

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7 January 2021

Labeling of fusion proteins with synthetic fluorophores in live cells

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7 January 2021

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Viral immune evasion due to persistence of activated T cells without effector function

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Cutting edge: TIGIT has T cell-intrinsic inhibitory functions

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

The TIGIT/CD226 axis regulates human T cell function

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021

Restoring immune function of tumor-specific CD4+ T cells during recurrence of melanoma

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7 January 2021

Cutting edge: DNAX accessory molecule 1-deficient CD8+ T cells display immunological synapse defects that impair antitumor immunity

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https://api.crossref.org/works/10.1016%2FJ.CCELL.2014.10.018

7 January 2021