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SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
title
SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1
(English)
1 reference
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
author
Xingzhi Xu
series ordinal
4
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Europe PubMed Central
PMC publication ID
3302164
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
author name string
Xu Li
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1
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Europe PubMed Central
PMC publication ID
3302164
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
H Helen Lin
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2
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3302164
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Hanqing Chen
series ordinal
3
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3302164
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
Hsiu-Ming Shih
series ordinal
5
1 reference
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
David K Ann
series ordinal
6
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
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1 February 2020
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English
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publication date
27 April 2010
1 reference
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
published in
Science Signaling
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
volume
3
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stated in
Europe PubMed Central
PMC publication ID
3302164
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
issue
119
1 reference
stated in
Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
page(s)
ra32
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Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
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PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing
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RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia
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Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
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KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions
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19 March 2017
The KAP1 corepressor functions to coordinate the assembly of de novo HP1-demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression
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PubMed Central
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19 March 2017
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
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KRAB-containing zinc-finger repressor proteins
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SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
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19 March 2017
Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD
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19 March 2017
A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1
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Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential
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19 March 2017
Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells
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19 March 2017
Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1
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19 March 2017
Ubc9 sumoylation regulates SUMO target discrimination
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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19 March 2017
Structural basis for regulation of protein phosphatase 1 by inhibitor-2
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19 March 2017
Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes
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19 March 2017
Protein phosphatase 1--targeted in many directions
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19 March 2017
Protein kinase Cdelta-dependent and -independent signaling in genotoxic response to treatment of desferroxamine, a hypoxia-mimetic agent
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19 March 2017
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27 September 2017
DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases
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27 September 2017
A PP1-binding motif present in BRCA1 plays a role in its DNA repair function
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27 September 2017
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin
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PubMed Central
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27 September 2017
Phosphorylation at Ser473 regulates heterochromatin protein 1 binding and corepressor function of TIF1beta/KAP1.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
A novel ATM-dependent pathway regulates protein phosphatase 1 in response to DNA damage
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
Physical and functional interactions between STAT3 and KAP1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
Phosphorylation and functions of inhibitor-2 family of proteins
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
KAP1 dictates p53 response induced by chemotherapeutic agents via Mdm2 interaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
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27 September 2017
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
SUMO: a regulator of gene expression and genome integrity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Functional diversity of protein phosphatase-1, a cellular economizer and reset button
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
27 September 2017
Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
29 November 2018
Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
29 November 2018
Determinants of the nucleolar targeting of protein phosphatase-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
29 November 2018
DNA repair in mononuclear cells: role of serine/threonine phosphatases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3302164
retrieved
29 November 2018
KAP1 regulates type I interferon/STAT1-mediated IRF-1 gene expression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20424263
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1126/SCISIGNAL.2000781
1 reference
stated in
Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PMC publication ID
3302164
1 reference
stated in
Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
PubMed publication ID
20424263
1 reference
stated in
Europe PubMed Central
PMC publication ID
3302164
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20424263%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 February 2020
ResearchGate publication ID
43348415
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