(Q24309030)

GOA release 2020-03-11

drug binding

1 reference

GOA release 2020-03-11

author name string

Neil Moss

1

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Younggi Choi

2

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Derek Cogan

3

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Adam Flegg

4

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Andreas Kahrs

5

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Pui Loke

6

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Orietta Meyn

7

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Raj Nagaraja

8

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Spencer Napier

9

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Ashley Parker

10

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J Thomas Peterson

11

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Philip Ramsden

12

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Christopher Sarko

13

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Donna Skow

14

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Josh Tomlinson

15

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Heather Tye

16

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Mark Whitaker

Bioorganic & Medicinal Chemistry Letters

17

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language of work or name

English

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publication date

15 April 2009

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published in

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volume

19

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page(s)

2206-10

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issue

8

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cites work

A simple method for predicting serum protein binding of compounds from IC(50) shift analysis for in vitro assays.

1 reference

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Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-kappaB in cardiomyocytes

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Plasma protein binding affinity and its relationship to molecular structure: an in-silico analysis

1 reference

https://api.crossref.org/works/10.1016%2FJ.BMCL.2009.02.126

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Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist

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https://api.crossref.org/works/10.1016%2FJ.BMCL.2009.02.126

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RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist

1 reference

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5-HT(2B) receptors play a key role in mediating the excitatory effects of 5-HT in human colon in vitro

1 reference

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7 January 2021

Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation

1 reference

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Altered expression of a limited number of genes contributes to cardiac decompensation during chronic ventricular tachypacing in dogs.

1 reference

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Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FJ.BMCL.2009.02.126

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Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation: control of interleukin-6, interleukin-1beta, and tumor necrosis factor-alpha cytokine production by ventricular fibroblasts

1 reference

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Ablation of serotonin 5-HT(2B) receptors in mice leads to abnormal cardiac structure and function

1 reference

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Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice

1 reference

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Functions of serotonin in hypoxic pulmonary vascular remodeling

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The importance of plasma protein binding in drug discovery

1 reference

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The Emergence of Selective 5-HT2B Antagonists Structures, Activities and Potential Therapeutic Applications [General Reviews]

1 reference

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