(Q24310260)

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EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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EPH receptor A2

1 reference

GOA release 2020-03-11

response to growth factor

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GOA release 2020-03-11

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based on heuristic

inferred from title

Amitava Mukherjee

3

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1 February 2020

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Hui Miao

1

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1 February 2020

Da-Qiang Li

2

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1 February 2020

Hong Guo

4

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1 February 2020

Aaron Petty

5

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1 February 2020

Jennifer Cutter

6

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1 February 2020

James P Basilion

7

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1 February 2020

John Sedor

8

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1 February 2020

Jiong Wu

9

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1 February 2020

David Danielpour

10

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1 February 2020

Andrew E Sloan

11

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1 February 2020

Mark L Cohen

12

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1 February 2020

Bingcheng Wang

13

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1 February 2020

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1 July 2009

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1 February 2020

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1 February 2020

16

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Europe PubMed Central

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1 February 2020

1

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Europe PubMed Central

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1 February 2020

9-20

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

1 reference

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An integrated genomic analysis of human glioblastoma multiforme

1 reference

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19 March 2017

EphA2 is an essential mediator of UV radiation-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

AKT/PKB signaling: navigating downstream

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Akt/PKB regulates actin organization and cell motility via Girdin/APE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Cell migration: integrating signals from front to back

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Rho GTPases and the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Mechanisms and functions of Eph and ephrin signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

Multiple in vivo tyrosine phosphorylation sites in EphB receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

A novel putative tyrosine kinase receptor encoded by the eph gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

19 March 2017

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

1 reference

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7 April 2017

Tumour-cell invasion and migration: diversity and escape mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Eph-ephrin bidirectional signaling in physiology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Malignant astrocytic glioma: genetics, biology, and paths to treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Ras, PI(3)K and mTOR signalling controls tumour cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Eph receptor signalling casts a wide net on cell behaviour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

7 April 2017

Eph/ephrin signaling in epithelial development and homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

An actin-binding protein Girdin regulates the motility of breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Integrative biology of prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Activation of PI3K-Akt signaling pathway promotes prostate cancer cell invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Akt1 governs breast cancer progression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Big roles for small GTPases in the control of directed cell movement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Neuropathology for the neuroradiologist: palisades and pseudopalisades.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Feedback signaling controls leading-edge formation during chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

EphA2 as a novel molecular marker and target in glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

A conditional feedback loop regulates Ras activity through EphA2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Diverse roles of eph receptors and ephrins in the regulation of cell migration and tissue assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

1 reference

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27 September 2017

Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Diverse roles for the Eph family of receptor tyrosine kinases in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Akt1 induces extracellular matrix invasion and matrix metalloproteinase-2 activity in mouse mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

27 September 2017

Eph receptors and ephrin ligands: embryogenesis to tumorigenesis

1 reference

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27 September 2017

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin

1 reference

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30 May 2018

Migrating glioma cells activate the PI3-K pathway and display decreased susceptibility to apoptosis

1 reference

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30 May 2018

Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration

1 reference

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29 November 2018

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1 reference

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29 November 2018

Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas

1 reference

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29 November 2018

Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

29 November 2018

EphA2 overexpression causes tumorigenesis of mammary epithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2860958

29 November 2018

Akt mediates Rac/Cdc42-regulated cell motility in growth factor-stimulated cells and in invasive PTEN knockout cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19573808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19573808

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CCR.2009.04.009

2 references

Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19573808%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

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