(Q24313100)

1

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D Cefai

2

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H Schneider

3

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M Raab

4

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N Nabavi

5

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C E Rudd

Inhibition of CD28-mediated T cell costimulation by the phosphoinositide 3-kinase inhibitor wortmannin

6

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language of work or name

English

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publication date

October 1995

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published in

Immunity

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volume

3

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page(s)

417-26

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issue

4

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cites work

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Phosphatidylinositol 3-kinase activity is not essential for CD28 costimulatory activity in Jurkat T cells: studies with a selective inhibitor, wortmannin

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

p21ras mediates control of IL-2 gene promoter function in T cell activation.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

PI 3-kinase is a dual specificity enzyme: autoregulation by an intrinsic protein-serine kinase activity.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

JNK is involved in signal integration during costimulation of T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Two-step TCR zeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Mechanisms of CD28 signalling

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Molecules involved in T-cell costimulation

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Absence of B7-dependent responses in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

B70 antigen is a second ligand for CTLA-4 and CD28.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Comparative analysis of B7-1 and B7-2 costimulatory ligands: expression and function

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

CTLA-4 binding to the lipid kinase phosphatidylinositol 3-kinase in T cells

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Long-term survival of xenogeneic pancreatic islet grafts induced by CTLA4lg

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Immunosuppression in vivo by a soluble form of the CTLA-4 T cell activation molecule

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The Son of sevenless Gene Product: a Putative Activator of Ras

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Regulation of Interleukin-2 Gene Enhancer Activity by the T Cell Accessory Molecule CD28

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Identification of an alternative CTLA-4 ligand costimulatory for T cell activation

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Uncovering of functional alternative CTLA-4 counter-receptor in B7-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex: the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The T-cell antigen CD5 acts as a receptor and substrate for the protein-tyrosine kinase p56lck

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

SR alpha promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

The role of the CD28 receptor during T cell responses to antigen

1 reference

https://api.crossref.org/works/10.1016%2F1074-7613%2895%2990171-X

7 January 2021

10.1016/1074-7613(95)90171-X

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1644199

1644199

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference