(Q24315036)

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Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative

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Direct activation of the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by an inducible mitogen-activated protein Kinase/ERK kinase kinase 3 (MEKK) derivative (English)

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mitogen-activated protein kinase kinase kinase 3

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GOA release 2020-03-11

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GOA release 2020-03-11

author name string

H Ellinger-Ziegelbauer

1

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K Brown

2

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K Kelly

3

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U Siebenlist

4

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language of work or name

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publication date

31 January 1997

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Journal of Biological Chemistry

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272

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5

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2668-74

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Diversity in function and regulation of MAP kinase pathways

1 reference

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21 January 2018

MAPKs: new JNK expands the group

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21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

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21 January 2018

MAP kinase pathways in yeast: for mating and more

1 reference

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21 January 2018

Parallel signal processing among mammalian MAPKs

1 reference

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21 January 2018

Rho family members: Activators of MAP kinase cascades

1 reference

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21 January 2018

ERKs, extracellular signal-regulated MAP-2 kinases

1 reference

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21 January 2018

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1 reference

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21 January 2018

JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

The stress-activated protein kinase subfamily of c-Jun kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

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21 January 2018

Characterization of the structure and function of a novel MAP kinase kinase (MKK6)

1 reference

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21 January 2018

MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade

1 reference

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21 January 2018

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

1 reference

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21 January 2018

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

1 reference

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21 January 2018

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Activation of Raf as a result of recruitment to the plasma membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Receptor tyrosine kinases and their targets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Complexity of the primary genetic response to mitogenic activation of human T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Development of a highly efficient expression cDNA cloning system: application to oncogene isolation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Rapid induction of heparin-binding epidermal growth factor/diphtheria toxin receptor expression by Raf and Ras oncogenes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Hormone-dependent transcriptional regulation and cellular transformation by Fos-steroid receptor fusion proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

MEK kinase is involved in tumor necrosis factor alpha-induced NF-kappaB activation and degradation of IkappaB-alpha.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

c-Jun N-terminal phosphorylation correlates with activation of the JNK subgroup but not the ERK subgroup of mitogen-activated protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

1 reference

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A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Transforming G protein-coupled receptors potently activate JNK (SAPK). Evidence for a divergence from the tyrosine kinase signaling pathway.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

21 January 2018

Raf-1 is required for T cell IL2 production.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective interaction of JNK protein kinase isoforms with transcription factors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Jun N-terminal kinase but not mitogen-activated protein kinase is sensitive to cAMP inhibition in T lymphocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning, characterization, and modeling of mouse and human guanylate kinases

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The MAPK signaling cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.272.5.2668

7 January 2021

based on heuristic

inferred from DOI database lookup

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