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Interaction between the retinoblastoma protein and the oncoprotein MDM2
scientific article
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instance of
scholarly article
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title
Interaction between the retinoblastoma protein and the oncoprotein MDM2
(English)
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main subject
MDM2 proto-oncogene
1 reference
stated in
GOA release 2020-03-11
positive regulation of cell population proliferation
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stated in
GOA release 2020-03-11
retinoblastoma
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based on heuristic
inferred from title
author name string
Z X Xiao
series ordinal
1
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J Chen
series ordinal
2
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A J Levine
series ordinal
3
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N Modjtahedi
series ordinal
4
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J Xing
series ordinal
5
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W R Sellers
series ordinal
6
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D M Livingston
series ordinal
7
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language of work or name
English
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publication date
22 June 1995
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published in
Nature
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volume
375
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page(s)
694-8
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issue
6533
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cites work
The p53 tumour suppressor gene
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor genes
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperative tumorigenic effects of germline mutations in Rb and p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the p53 and mdm-2 interaction domains
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a growth suppression domain within the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regions of the retinoblastoma gene product required for its interaction with the E2F transcription factor are necessary for E2 promoter repression and pRb-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor E2F-1 is a downstream target of RB action
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protein synthesis-dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
E2F-1-mediated transactivation is inhibited by complex formation with the retinoblastoma susceptibility gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and E2F-1 cooperate to mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F375694A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/375694A0
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3705724
Dimensions Publication ID
1043400439
0 references
OpenCitations bibliographic resource ID
3705724
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3705724
PubMed ID
7791904
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
3705724
Springer Nature article ID
10.1038/375694a0
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