(Q24324515)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

AlkB homolog 2, alpha-ketoglutarate dependent dioxygenase

6 January 2020

main subject

crystal structure

0 references

1 reference

cytosine C-5 DNA demethylase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Chengqi Yi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Xing Jian

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

author name string

Cai-Guang Yang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Erica M Duguid

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Christopher T Sullivan

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Phoebe A Rice

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

Chuan He

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

language of work or name

English

0 references

publication date

1 April 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

number of pages

5

1 reference

inferred from page(s)

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

452

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

page(s)

961-965

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

issue

7190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

6 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Defective processing of methylated single-stranded DNA by E. coli AlkB mutants

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Enzymatic capture of an extrahelical thymine in the search for uracil in DNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Structural basis for removal of adenine mispaired with 8-oxoguanine by MutY adenine DNA glycosylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

19 March 2017

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision

19 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

19 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Repair of methylation damage in DNA and RNA by mammalian AlkB homologues

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Regulation and expression of the adaptive response to alkylating agents

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Structure of a DNA glycosylase searching for lesions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Repairing DNA-methylation damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Covalent trapping of protein-DNA complexes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Reversal of DNA alkylation damage by two human dioxygenases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

27 September 2017

Human DNA repair genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Oxygen activating nonheme iron enzymes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

How Do DNA Repair Proteins Locate Potential Base Lesions? A Chemical Crosslinking Method to Investigate O6-Alkylguanine-DNA Alkyltransferases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2587245

Rapid automated molecular replacement by evolutionary search

29 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Coot: model-building tools for molecular graphics

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Automated MAD and MIR structure solution

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1038%2FNATURE06889

7 January 2021

Identifiers

DOI

10.1038/NATURE06889

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 January 2020

1000195406

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18432238%20AND%20SRC:MED&resulttype=core&format=json