(Q24324618)

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PKHD1 gene silencing may cause cell abnormal proliferation through modulation of intracellular calcium in autosomal recessive polycystic kidney disease

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scholarly article

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PKHD1 gene silencing may cause cell abnormal proliferation through modulation of intracellular calcium in autosomal recessive polycystic kidney disease (English)

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autosomal recessive polycystic kidney

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PKHD1 ciliary IPT domain containing fibrocystin/polyductin

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GOA release 2020-03-11

regulation of ERK1 and ERK2 cascade

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GOA release 2020-03-11

author name string

Jiyun Yang

1

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Sizhong Zhang

2

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Qin Zhou

3

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Hong Guo

4

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Ke Zhang

5

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Rong Zheng

6

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Cuiying Xiao

7

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language of work or name

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publication date

31 July 2007

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40

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4

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467-74

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PKHD1 mutations in autosomal recessive polycystic kidney disease (ARPKD).

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

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A novel gene encoding a TIG multiple domain protein is a positional candidate for autosomal recessive polycystic kidney disease

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Autosomal recessive polycystic kidney disease

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Bending the MDCK cell primary cilium increases intracellular calcium

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Removal of the MDCK cell primary cilium abolishes flow sensing

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Autosomal recessive polycystic kidney disease: long-term outcome of neonatal survivors

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of ERK1/2 signaling during EGF-induced inhibition of palatal fusion

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of Ca(2+)-dependent transcription

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https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Rational siRNA design for RNA interference

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Mapping of the gene for autosomal recessive polycystic kidney disease (ARPKD) to chromosome 6p21-cen

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

SET-induced calcium signaling and MAPK/ERK pathway activation mediate dendritic cell-like differentiation of U937 cells

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of polycystic kidney disease with a novel tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

The frequencies of calcium oscillations are optimized for efficient calcium-mediated activation of Ras and the ERK/MAPK cascade.

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcium-activated RAF/MEK/ERK signaling pathway mediates p53-dependent apoptosis and is abrogated by alpha B-crystallin through inhibition of RAS activation

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia.

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Autosomal recessive polycystic kidney disease in adulthood

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

EGF-related growth factors in the pathogenesis of murine ARPKD.

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Clinical consequences of PKHD1 mutations in 164 patients with autosomal-recessive polycystic kidney disease (ARPKD)

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Autosomal recessive polycystic kidney disease in 115 children: clinical presentation, course and influence of gender. Arbeitsgemeinschaft für Pädiatrische, Nephrologie

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for ERK1/2 in EGF- and ATP-dependent regulation of amiloride-sensitive sodium absorption

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Abnormal EGF-dependent regulation of sodium absorption in ARPKD collecting duct cells

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanoregulation of intracellular Ca2+ concentration is attenuated in collecting duct of monocilium-impaired orpk mice

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

H2O2-induced transactivation of EGF receptor requires Src and mediates ERK1/2, but not Akt, activation in renal cells

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

inferred from DOI database lookup

Epidermal growth factor receptor activity mediates renal cyst formation in polycystic kidney disease

1 reference

https://api.crossref.org/works/10.5483%2FBMBREP.2007.40.4.467

7 January 2021

based on heuristic

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The BDNF gene: exemplifying complexity in Ca2+ -dependent gene expression.

1 reference

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7 January 2021

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Prevalence of abnormal urinary albumin excretion rate in hypertensive patients with impaired fasting glucose and its association with cardiovascular disease

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based on heuristic

inferred from DOI database lookup

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10.5483/BMBREP.2007.40.4.467

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