(Q24337213)

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Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells

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scholarly article

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Protein phosphorylation profiling using an in situ proximity ligation assay: phosphorylation of AURKA-elicited EGFR-Thr654 and EGFR-Ser1046 in lung cancer cells (English)

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phosphorylation

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author name string

Tzu-Chi Chen

1

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Yu-Wen Liu

2

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Yei-Hsuan Huang

3

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Yi-Chen Yeh

4

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Teh-Ying Chou

5

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Yu-Chung Wu

6

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Chun-Chi Wu

7

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Yi-Rong Chen

8

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Hui-Chuan Cheng

9

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Pei-Jung Lu

10

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Jin-Mei Lai

11

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Chi-Ying F Huang

12

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language of work or name

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publication date

2013

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8

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e55657

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3

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copyright license

Creative Commons Attribution 4.0 International

8 March 2013

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April 2022 Public Data File from Crossref

copyright status

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PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse

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19 March 2017

The Hallmarks of Cancer

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19 March 2017

The Croonian Lecture 1997. The phosphorylation of proteins on tyrosine: its role in cell growth and disease

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19 March 2017

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

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19 March 2017

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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19 March 2017

Untangling the ErbB signalling network

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19 March 2017

Cell signaling by receptor tyrosine kinases

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19 March 2017

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

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19 March 2017

Global analysis of protein activities using proteome chips

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19 March 2017

The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation

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19 March 2017

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

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19 March 2017

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

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19 March 2017

Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase

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19 March 2017

Cancer statistics, 2009

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7 April 2017

Erlotinib in previously treated non-small-cell lung cancer

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7 April 2017

Direct observation of individual endogenous protein complexes in situ by proximity ligation

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7 April 2017

The ErbB signaling network: receptor heterodimerization in development and cancer

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7 April 2017

TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.

1 reference

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27 September 2017

Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Translational up-regulation of Aurora-A in EGFR-overexpressed cancer

1 reference

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27 September 2017

Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

ErbB receptors and signaling pathways in cancer

1 reference

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27 September 2017

Ligand-induced ErbB receptor dimerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Aurora kinases as anticancer drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

High-throughput mutational analysis of the human cancer genome

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27 September 2017

Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Molecular dynamics of Aurora-A kinase in living mitotic cells simultaneously visualized with histone H3 and nuclear membrane protein importinalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

EGFR and cancer prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

The centrosome in vertebrates: more than a microtubule-organizing center

1 reference

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27 September 2017

A negative feedback loop attenuates EGF-induced morphological changes

1 reference

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27 September 2017

Independent mechanisms account for the regulation by protein kinase C of the epidermal growth factor receptor affinity and tyrosine-protein kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

27 September 2017

Personalized medicine and inhibition of EGFR signaling in lung cancer

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30 May 2018

TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling

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30 May 2018

Distinctive activation patterns in constitutively active and gefitinib-sensitive EGFR mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

30 May 2018

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

1 reference

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30 May 2018

Mechanism of phosphorylation of the epidermal growth factor receptor at threonine 669.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

30 May 2018

Phosphorylation of the epidermal growth factor receptor at threonine 654 inhibits ligand-induced internalization and down-regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

30 May 2018

Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055657

21 January 2018

High frequency of epidermal growth factor receptor mutations with complex patterns in non-small cell lung cancers related to gefitinib responsiveness in Taiwan

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055657

21 January 2018

Gene expression profiles of the aurora family kinases.

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055657

21 January 2018

Quantitation of Multisite EGF Receptor Phosphorylation Using Mass Spectrometry and a Novel Normalization Approach

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055657

21 January 2018

The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

29 November 2018

Epidermal growth factor receptor expression correlates with poor prognosis in non-small cell lung cancer patients with p53 overexpression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3592865

29 November 2018

Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055657

21 January 2018

Transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor-alpha through the TAK1-p38 signaling pathway

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12 December 2020

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Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer

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https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

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Phospho-regulation of human protein kinase Aurora-A: analysis using anti-phospho-Thr288 monoclonal antibodies

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https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

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Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

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Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroendocrine bronchial and thymic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/23520446

12 December 2020

based on heuristic

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Identifiers

10.1371/JOURNAL.PONE.0055657

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2013PLoSO...855657C

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