(Q24337271)

English

Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers

scientific article

In more languages

Statements

scholarly article

0 references

Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers (English)

0 references

Nuclear receptor subfamily 0 group B member 2

1 reference

GOA release 2020-03-11

Nuclear receptor subfamily 0 group B member 1

1 reference

GOA release 2020-03-11

protein homodimerization activity

1 reference

GOA release 2020-03-11

author name string

Anita K Iyer

1

0 references

Yao-Hua Zhang

2

0 references

Edward R B McCabe

3

0 references

language of work or name

0 references

publication date

October 2006

0 references

Molecular Endocrinology

0 references

20

0 references

10

0 references

2326-42

0 references

Transcriptional profiling of human osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of DAX-1, the gene responsible for X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism, in the hypothalamic-pituitary-adrenal/gonadal axis

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Ligand- and DNA-induced dissociation of RXR tetramers 1 1Edited by M. Yaniv

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Consequences of complexity within biological networks: robustness and health, or vulnerability and disease

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Nr0b1 and its network partners are expressed early in murine embryos prior to steroidogenic axis organogenesis

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

DAX1 and its network partners: exploring complexity in development

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanisms of DAX1 action

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

NR0B1A: an alternatively spliced form of NR0B1.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic network identification by high density, multiplexed reversed transcriptional (HD-MRT) analysis in steroidogenic axis model cell lines

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Characterization of the interaction between androgen receptor and a new transcriptional inhibitor, SHP.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

SHP represses transcriptional activity via recruitment of histone deacetylases.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid receptor mutants into the nucleus

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The orphan nuclear receptor SHP inhibits agonist-dependent transcriptional activity of estrogen receptors ERalpha and ERbeta

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Interaction of the corepressor Alien with DAX-1 is abrogated by mutations of DAX-1 involved in adrenal hypoplasia congenita

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

DAX-1 functions as an LXXLL-containing corepressor for activated estrogen receptors

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

FXXLF and WXXLF sequences mediate the NH2-terminal interaction with the ligand binding domain of the androgen receptor

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Small heterodimer partner, an orphan nuclear receptor, augments peroxisome proliferator-activated receptor gamma transactivation

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucocorticoid signaling is perturbed by the atypical orphan receptor and corepressor SHP

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRgamma

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

An orphan nuclear hormone receptor that lacks a DNA binding domain and heterodimerizes with other receptors

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Novel receptor interaction and repression domains in the orphan receptor SHP.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Orphan receptor DAX-1 is a shuttling RNA binding protein associated with polyribosomes via mRNA

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The orphan nuclear receptor SHP utilizes conserved LXXLL-related motifs for interactions with ligand-activated estrogen receptors

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Glucocorticoid receptor homodimers and glucocorticoid-mineralocorticoid receptor heterodimers form in the cytoplasm through alternative dimerization interfaces

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

LXXLL-related motifs in Dax-1 have target specificity for the orphan nuclear receptors Ad4BP/SF-1 and LRH-1.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear hormone receptors and gene expression

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Adrenal hypoplasia congenita with hypogonadotropic hypogonadism: evidence that DAX-1 mutations lead to combined hypothalmic and pituitary defects in gonadotropin production

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Steroidogenic Factor 1: A Key Determinant of Endocrine Development and Function

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of the LXXLL-motif and activation function 2 domain in subcellular localization of Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1)

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The small heterodimer partner interacts with the pregnane X receptor and represses its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase A potentiates adrenal 4 binding protein/steroidogenic factor 1 transactivation by reintegrating the subcellular dynamic interactions of the nuclear receptor with its cofactors, general control nonderepressed-5/transformation/transcrip

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Generation of two distinct functional isoforms of dosage-sensitive sex reversal-adrenal hypoplasia congenita-critical region on the X chromosome gene 1 (DAX-1) by alternative splicing

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

The atypical orphan nuclear receptor DAX-1 interacts with orphan nuclear receptor Nur77 and represses its transactivation

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Negative cross-talk between Nur77 and small heterodimer partner and its role in apoptotic cell death of hepatoma cells.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Estrogen receptor alpha and beta heterodimers exert unique effects on estrogen- and tamoxifen-dependent gene expression in human U2OS osteosarcoma cells.

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of estrogen receptor action by the orphan receptor SHP (short heterodimer partner)

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1

1 reference

https://api.crossref.org/works/10.1210%2FME.2005-0383

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1210/ME.2005-0383

0 references

release_o7lix2hgufcsnfbyiursmusfmq

1 reference

https://api.fatcat.wiki/v0/release/o7lix2hgufcsnfbyiursmusfmq

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q24337271&oldid=1951009776"