(Q24338156)

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Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block

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scholarly article

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Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block (English)

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congenital disorder

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GOA release 2020-03-11

cardiac conduction system development

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GOA release 2020-03-11

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GOA release 2020-03-11

congenital heart disease

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based on heuristic

inferred from title

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author name string

Mohammad Pashmforoush

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Jonathan T Lu

2

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Hanying Chen

3

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Tara St Amand

4

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Richard Kondo

5

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Sylvain Pradervand

6

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Sylvia M Evans

7

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Bob Clark

8

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James R Feramisco

9

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Wayne Giles

10

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Siew Yen Ho

11

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D Woodrow Benson

12

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Michael Silberbach

13

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Weinian Shou

14

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Kenneth R Chien

15

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language of work or name

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publication date

30 April 2004

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117

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373-86

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3

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Fluorescence microscopy in three dimensions.

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Anatomic criteria for identifying the components of the axis responsible for atrioventricular conduction

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A combined morphological and electrophysiological study of the atrioventricular node of the rabbit heart

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Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways

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Transcriptional regulation of vertebrate cardiac morphogenesis

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

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Hop is an unusual homeobox gene that modulates cardiac development

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BMP10 is essential for maintaining cardiac growth during murine cardiogenesis

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Cardiac homeobox gene NKX2-5 mutations and congenital heart disease: associations with atrial septal defect and hypoplastic left heart syndrome.

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Developing models of DiGeorge syndrome

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Molecular characterization of the ventricular conduction system in the developing mouse heart: topographical correlation in normal and congenitally malformed hearts

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GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

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Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor

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NKX2.5 mutations in patients with tetralogy of fallot

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Progressive AV-block and anomalous venous return among cardiac anomalies associated with two novel missense mutations in the CSX/NKX2-5 gene

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Comparison of ion-channel subunit expression in canine cardiac Purkinje fibers and ventricular muscle

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Homeodomain factor Nkx2-5 in heart development and disease

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Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

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How constant anatomically is the tendon of Todaro as a marker for the triangle of Koch?

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Development of the Cardiac Conduction System as Delineated by minK‐lacZ

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Replacement by homologous recombination of the minK gene with lacZ reveals restriction of minK expression to the mouse cardiac conduction system.

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Requirement for neuregulin receptor erbB2 in neural and cardiac development

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5

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Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling.

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Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily

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A novel genetic pathway for sudden cardiac death via defects in the transition between ventricular and conduction system cell lineages

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Ventricular noncompaction and distal chromosome 5q deletion

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Cre-constructing the heart

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Congenital heart disease caused by mutations in the transcription factor NKX2-5

1 reference

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Spatiotemporal pattern of commitment to slowed proliferation in the embryonic mouse heart indicates progressive differentiation of the cardiac conduction system.

1 reference

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Modulation of cardiac growth and development by HOP, an unusual homeodomain protein

1 reference

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1 reference

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10.1016/S0092-8674(04)00405-2

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