(Q24339513)

2

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Yue Zhang

3

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Yan Zhang

4

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Lifang Ma

5

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Wenhao Weng

6

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Yongxia Qiao

7

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Weifan Xiao

8

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Hongmei Wang

9

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Wenjun Yu

10

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Qiuhui Pan

11

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Yunyan He

12

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Fenyong Sun

Hepatocellular carcinoma pathogenesis: from genes to environment

13

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language of work or name

English

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publication date

11 December 2013

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published in

FEBS Letters

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volume

587

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issue

24

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page(s)

3921-7

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cites work

1 reference

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Yes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinoma

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Mutual interaction between YAP and CREB promotes tumorigenesis in liver cancer

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Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway

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Multiple anticancer effects of blocking MEK-ERK signaling in hepatocellular carcinoma

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Hepatitis C virus core protein enhances the activation of the transcription factor, Elk1, in response to mitogenic stimuli

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Hepatitis C virus core protein activates the MAPK/ERK cascade synergistically with tumor promoter TPA, but not with epidermal growth factor or transforming growth factor alpha

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Hepatitis B virus X protein modulates oncogene Yes-associated protein by CREB to promote growth of hepatoma cells.

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TEAD mediates YAP-dependent gene induction and growth control

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The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain

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Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs

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The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models

21 January 2018

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A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

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TRIB2 acts downstream of Wnt/TCF in liver cancer cells to regulate YAP and C/EBPα function

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β-TrCP-mediated IRAK1 degradation releases TAK1-TRAF6 from the membrane to the cytosol for TAK1-dependent NF-κB activation

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Ubiquitylation of the amino terminus of Myc by SCF(β-TrCP) antagonizes SCF(Fbw7)-mediated turnover

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Transformation of mammalian cells by constitutively active MAP kinase kinase

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inferred from DOI database lookup

7 January 2021

based on heuristic

MEK1/2 inhibition enhances the radiosensitivity of cancer cells by downregulating survival and growth signals mediated by EGFR ligands

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