(Q24531220)

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The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma

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The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinoma (English)

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hepatocellular carcinoma

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based on heuristic

inferred from title

author name string

Maryann E Smela

1

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Michelle L Hamm

2

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Paul T Henderson

3

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Constance M Harris

4

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Thomas M Harris

5

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John M Essigmann

6

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language of work or name

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publication date

14 May 2002

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Proceedings of the National Academy of Sciences of the United States of America

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99

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10

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6655-60

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Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

Aflatoxin B1 induces the transversion of G-->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

An intercalated and thermally stable FAPY adduct of aflatoxin B1 in a DNA duplex: structural refinement from 1H NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

Refined Solution Structure of 8,9-Dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B1 opposite CpA in the Complementary Strand of an Oligodeoxynucleotide Duplex As Determined by 1H NMR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

Genetic alterations during colorectal-tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

24 March 2017

The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

The SOS response: recent insights into umuDC-dependent mutagenesis and DNA damage tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Plasmid-encoded MucB protein is a DNA polymerase (pol RI) specialized for lesion bypass in the presence of MucA', RecA, and SSB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Intrinsic polymerase activities of UmuD'(2)C and MucA'(2)B are responsible for their different mutagenic properties during bypass of a T-T cis-syn cyclobutane dimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Multiple mutations in a shuttle vector modified by ultraviolet irradiation, (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene, and aflatoxin B(1) have different properties than single mutations and may be genera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

A viral genome containing an unstable aflatoxin B1-N7-guanine DNA adduct situated at a unique site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Mutational properties of the primary aflatoxin B1-DNA adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Substitution of mucAB or rumAB for umuDC alters the relative frequencies of the two classes of mutations induced by a site-specific T-T cyclobutane dimer and the efficiency of translesion DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Characterization of the umu-complementing operon from R391.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Excision repair of aflatoxin B1-DNA adducts in human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

In vitro reactions of aflatoxin B1-adducted DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Two rotameric forms of open ring 7-methylguanine are present in alkylated polynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Base substitution mutations induced by metabolically activated aflatoxin B1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Sequence specificity in aflatoxin B1--DNA interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Sequence context effects in DNA replication blocks induced by aflatoxin B1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Induction of base substitution mutations by aflatoxin B1 is mucAB dependent in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Identification of an activated c-Ki-ras oncogene in rat liver tumors induced by aflatoxin B1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Carcinogen-nucleic acid interactions: equilibrium binding studies of aflatoxin B1 with the oligodeoxynucleotide d(ATGCAT)2 and with plasmid pBR322 support intercalative association with the B-DNA helix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Site-specifically alkylated oligodeoxynucleotides: probes for mutagenesis, DNA repair and the structural effects of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Mutation frequency and spectrum resulting from a single abasic site in a single-stranded vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

SOS-dependent replication past a single trans-syn T-T cyclobutane dimer gives a different mutation spectrum and increased error rate compared with replication past this lesion in uninduced cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Intercalation of aflatoxin B1 in two oligodeoxynucleotide adducts: comparative 1H NMR analysis of d(ATCAFBGAT).d(ATCGAT) and d(ATAFBGCAT)2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

The enhanced mutagenic potential of the MucAB proteins correlates with the highly efficient processing of the MucA protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

27 September 2017

In vitro activation of the human Harvey-ras proto-oncogene by aflatoxin B1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Preferential binding of aflatoxin B1 to the transcriptionally active regions of rat liver nucleolar chromatin in vivo and in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Mechanisms of mutagenesis by a bulky DNA lesion at the guanine N7 position.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Reaction of acid-activated mitomycin C with calf thymus DNA and model guanines: elucidation of the base-catalyzed degradation of N7-alkylguanine nucleosides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Comparative binding and sequence interaction specificities of aflatoxin B1, aflatoxicol, aflatoxin M1, and aflatoxicol M1 with purified DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Mapping the binding site of aflatoxin B1 in DNA: systematic analysis of the reactivity of aflatoxin B1 with guanines in different DNA sequences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Induction and cleavage of Salmonella typhimurium UmuD protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Sequence specificity of aflatoxin B1-induced mutations in a plasmid replicated in xeroderma pigmentosum and DNA repair proficient human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Quantitative comparison of covalent aflatoxin-DNA adducts formed in rat and mouse livers and kidneys.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Construction of a umuDC operon substitution mutation in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

30 May 2018

Quantitation and mapping of aflatoxin B1-induced DNA damage in genomic DNA using aflatoxin B1-8,9-epoxide and microsomal activation systems

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102167699

21 January 2018

The appearance of the UmuD'C protein complex in Escherichia coli switches repair from homologous recombination to SOS mutagenesis.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102167699

21 January 2018

DNA-directed aniline mustards with high selectivity for adenine or guanine bases: mutagenesis in a variety of Salmonella typhimurium strains differing in DNA-repair capability.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102167699

21 January 2018

Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: I. Frameshift mutagenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124458

29 November 2018

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102167699

21 January 2018

Aflatoxin B -oxide generated by chemical or enzymic oxidation of aflatoxin B1 causes guanine substitution in nucleic acids

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.102167699

21 January 2018

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal patterns of covalent DNA adducts in rat liver after single and multiple doses of aflatoxin B1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkaline opening of imidazole ring of 7-methylguanosine. 1. Analysis of the resulting pyrimidine derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alkaline opening of imidazole ring of 7-methylguanosine. 2. Further studies on reaction mechanisms and products

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Covalent and noncovalent interactions of aflatoxin with defined deoxyribonucleic acid sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of SOS and MucAB functions on reactivation and mutagenesis of M13 replicative form DNA bearing bulky lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Base and sequence specificities of aflatoxin B1 binding to single- and double-stranded DNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro replication study of modified bases in ras sequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refined structure of the doubly intercalated d(TATAFBGCATA)2 aflatoxin B1 adduct

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of a site-specific trans-8,9-dihydro-8-(N7-guanyl)-9-hydroxyaflatoxin B(1) adduct by the exonuclease deficient klenow fragment of DNA polymerase I

1 reference

https://pubmed.ncbi.nlm.nih.gov/12011430

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.102167699

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2002PNAS...99.6655S

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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