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The hypocretin/orexin system
scientific article
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
The hypocretin/orexin system
(English)
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author name string
I O Ebrahim
series ordinal
1
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R S Howard
series ordinal
2
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M D Kopelman
series ordinal
3
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M K Sharief
series ordinal
4
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A J Williams
series ordinal
5
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language of work or name
English
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publication date
May 2002
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published in
Medico-Chirurgical Transactions
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stated in
PubMed
volume
95
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issue
5
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page(s)
227-30
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cites work
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
1 reference
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PubMed Central
reference URL
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24 March 2017
The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity
1 reference
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PubMed Central
reference URL
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24 March 2017
Overview of the most prevalent hypothalamus-specific mRNAs, as identified by directional tag PCR subtraction
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
24 March 2017
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
24 March 2017
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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24 March 2017
Distinct mechanism for antidepressant activity by blockade of central substance P receptors
1 reference
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PubMed Central
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24 March 2017
Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression
1 reference
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PubMed Central
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24 March 2017
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
7 April 2017
Neurons containing hypocretin (orexin) project to multiple neuronal systems
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
7 April 2017
The role of the hypothalamic neuropeptides hypocretin/orexin in the sleep-wake cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Research and treatment approaches to depression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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27 September 2017
Narcolepsy: new understanding of irresistible sleep
1 reference
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PubMed Central
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27 September 2017
Hypothalamic arousal regions are activated during modafinil-induced wakefulness.
1 reference
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PubMed Central
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27 September 2017
Reduced number of hypocretin neurons in human narcolepsy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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27 September 2017
Narcolepsy: a neurodegenerative disease of the hypocretin system?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
The hypocretins: excitatory neuromodulatory peptides for multiple homeostatic systems, including sleep and feeding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Hypothalamic hypocretin (orexin): robust innervation of the spinal cord
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Presynaptic and postsynaptic actions and modulation of neuroendocrine neurons by a new hypothalamic peptide, hypocretin/orexin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Norepinephrine in depressive reactions. A review
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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27 September 2017
The biochemistry of affective disorders
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
27 September 2017
Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
30 May 2018
The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
30 May 2018
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
30 May 2018
Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
30 May 2018
Hypocretin-1 (orexin-A) levels in human lumbar CSF in different age groups: infants to elderly persons.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Systemic administration of hypocretin-1 reduces cataplexy and normalizes sleep and waking durations in narcoleptic dogs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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29 November 2018
Neuroscience. The sandman's secrets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Both corticotropin releasing factor and neuropeptide Y are involved in the effect of orexin (hypocretin) on the food intake in rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
The hypocretin/orexin story.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Perspectives in narcolepsy and hypocretin (orexin) research.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Orexin synthesis and response in the gut.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Hypocretin (orexin) deficiency in human narcolepsy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Cardiovascular regulatory actions of the hypocretins in brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Distribution of orexin receptor mRNA in the rat brain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
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29 November 2018
Monoamine dysfunction and the pathophysiology and treatment of depression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1279673
retrieved
29 November 2018
Blunted Corticotropin and Normal Cortisol Response to Human Corticotropin-Releasing Factor in Depression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11983761
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypocretin deficiency in familial symptomatic narcolepsy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11983761
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11983761
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Centrally administered orexin/hypocretin activates HPA axis in rats
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/11983761
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1258/JRSM.95.5.227
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PMC publication ID
1279673
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PubMed publication ID
11983761
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ResearchGate publication ID
11385528
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