(Q24537482)

English

Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Haploinsufficiency of the Mus81-Eme1 endonuclease activates the intra-S-phase and G2/M checkpoints and promotes rereplication in human cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

haploinsufficiency

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author name string

Takashi Hiyama

1

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Mari Katsura

2

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Takashi Yoshihara

3

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Mari Ishida

4

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Aiko Kinomura

5

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Tetsuji Tonda

6

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Toshimasa Asahara

7

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Kiyoshi Miyagawa

8

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

language of work or name

0 references

publication date

2 February 2006

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

Nucleic Acids Research

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

34

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

880-892

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

RAD51C is required for Holliday junction processing in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Mus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

RNA interference inhibition of Mus81 reduces mitotic recombination in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Identification and characterization of human MUS81-MMS4 structure-specific endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

A role for RAD54B in homologous recombination in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Mad2 transiently associates with an APC/p55Cdc complex during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

A role for MMS4 in the processing of recombination intermediates during meiosis in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

MUS81 encodes a novel helix-hairpin-helix protein involved in the response to UV- and methylation-induced DNA damage in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Human Mus81-associated endonuclease cleaves Holliday junctions in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Caffeine inhibits the checkpoint kinase ATM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Generating crossovers by resolution of nicked Holliday junctions: a role for Mus81-Eme1 in meiosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Homologous recombinational repair of DNA ensures mammalian chromosome stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

24 March 2017

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

7 April 2017

Mus81-Eme1 are essential components of a Holliday junction resolvase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

7 April 2017

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

7 April 2017

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

7 April 2017

The DNA damage response during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Disruption of murine Mus81 increases genomic instability and DNA damage sensitivity but does not promote tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

DNA repair by a Rad22-Mus81-dependent pathway that is independent of Rhp51.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Checking on DNA damage in S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Detection of cyclin b1 expression in g(1)-phase cancer cell lines and cancer tissues by postsorting Western blot analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Caffeine and human DNA metabolism: the magic and the mystery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

DNA damage checkpoint control in cells exposed to ionizing radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

The Mechanism of Mus81-Mms4 Cleavage Site Selection Distinguishes It from the Homologous Endonuclease Rad1-Rad10

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Identification and characterization of the human mus81-eme1 endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Alternate pathways involving Sgs1/Top3, Mus81/ Mms4, and Srs2 prevent formation of toxic recombination intermediates from single-stranded gaps created by DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Rad51 accumulation at sites of DNA damage and in postreplicative chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Xrcc3 is required for assembly of Rad51 complexes in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Construction by gene targeting in human cells of a "conditional' CDC2 mutant that rereplicates its DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

27 September 2017

Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

30 May 2018

Involvement of mammalian Mus81 in genome integrity and tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

29 November 2018

Rad54, a Swi2/Snf2-like recombinational repair protein, disassembles Rad51:dsDNA filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

29 November 2018

Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

29 November 2018

Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1360746

29 November 2018

Stable association of mitotic cyclin B/Cdc2 to replication origins prevents endoreduplication

1 reference

https://pubmed.ncbi.nlm.nih.gov/16456034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endogenous Mus81-Eme1 complex resolves Holliday junctions by a nick and counternick mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/16456034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gross Chromosomal Rearrangements and Elevated Recombination at an Inducible Site-Specific Replication Fork Barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/16456034

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKJ495

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 July 2017

ResearchGate publication ID

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