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Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis
scientific article
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
title
Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
main subject
infectious disease
0 references
author
Alessandra S Eustáquio
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Lutz Heide
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Anthony Maxwell
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
author name string
Ruth H Flatman
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
Shu-Ming Li
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
language of work or name
English
0 references
publication date
1 April 2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
number of pages
7
1 reference
based on heuristic
inferred from page(s)
published in
Antimicrobial Agents and Chemotherapy
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
volume
50
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
issue
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
page(s)
1136-1142
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
cites work
The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
24 March 2017
The ATP-binding site of type II topoisomerases as a target for antibacterial drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
24 March 2017
New aminocoumarin antibiotics from genetically engineered Streptomyces strains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Antimicrobial and DNA gyrase-inhibitory activities of novel clorobiocin derivatives produced by mutasynthesis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Resistance genes of aminocoumarin producers: two type II topoisomerase genes confer resistance against coumermycin A1 and clorobiocin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Fluoroquinolones: action and resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Quinolone-binding pocket of DNA gyrase: role of GyrB.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Improved antibacterial activities of coumarin antibiotics bearing 5',5'-dialkylnoviose: biological activity of RU79115.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
DNA gyrase as a drug target
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
27 September 2017
Heterologous expression of novobiocin and clorobiocin biosynthetic gene clusters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
30 May 2018
DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
30 May 2018
The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
30 May 2018
Expression and analysis of two gyrB genes from the novobiocin producer, Streptomyces sphaeroides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
30 May 2018
Metabolic engineering of aminocoumarins: inactivation of the methyltransferase gene cloP and generation of new clorobiocin derivatives in a heterologous host
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Identification of a topoisomerase IV in actinobacteria: purification and characterization of ParYR and GyrBR from the coumermycin A1 producer Streptomyces rishiriensis DSM 40489.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
CloN2, a novel acyltransferase involved in the attachment of the pyrrole-2-carboxyl moiety to the deoxysugar of clorobiocin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Clorobiocin biosynthesis in Streptomyces: identification of the halogenase and generation of structural analogs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Synthesis and in vitro evaluation of novel highly potent coumarin inhibitors of gyrase B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Tryptic fragments of the Escherichia coli DNA gyrase A protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1426943
retrieved
29 November 2018
Overexpression and purification of bacterial DNA gyrase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1128%2FAAC.50.4.1136-1142.2006
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1128/AAC.50.4.1136-1142.2006
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PMC publication ID
1426943
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
PubMed publication ID
16569821
1 reference
stated in
Europe PubMed Central
PMC publication ID
1426943
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16569821%20AND%20SRC:MED&resulttype=core&format=json
retrieved
18 January 2020
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