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Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2
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title
Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2
(English)
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author name string
C H Yam
series ordinal
1
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R W Ng
series ordinal
2
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W Y Siu
series ordinal
3
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A W Lau
series ordinal
4
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R Y Poon
series ordinal
5
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language of work or name
English
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publication date
January 1999
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published in
Molecular and Cellular Biology
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volume
19
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issue
1
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page(s)
635-45
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cites work
Association of human CUL-1 and ubiquitin-conjugating enzyme CDC34 with the F-box protein p45(SKP2): evidence for evolutionary conservation in the subunit composition of the CDC34-SCF pathway
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New functional activities for the p21 family of CDK inhibitors
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Mammalian p50Cdc37 is a protein kinase-targeting subunit of Hsp90 that binds and stabilizes Cdk4
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Human cyclin F
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24 March 2017
p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase
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PubMed Central
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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
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PubMed Central
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24 March 2017
F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex
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PubMed Central
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Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins
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PubMed Central
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24 March 2017
Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression
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PubMed Central
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24 March 2017
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
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24 March 2017
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae
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24 March 2017
Identification of functional domains in the neuronal Cdk5 activator protein
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24 March 2017
Cyclin-dependent kinases are inactivated by a combination of p21 and Thr-14/Tyr-15 phosphorylation after UV-induced DNA damage
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24 March 2017
Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2)
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PubMed Central
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24 March 2017
Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
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24 March 2017
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
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PubMed Central
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24 March 2017
Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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24 March 2017
p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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24 March 2017
Cyclin-dependent kinases: engines, clocks, and microprocessors
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PubMed Central
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7 April 2017
Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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7 April 2017
Distinct roles for cyclin-dependent kinases in cell cycle control
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PubMed Central
reference URL
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7 April 2017
Human CUL1 forms an evolutionarily conserved ubiquitin ligase complex (SCF) with SKP1 and an F-box protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
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PubMed Central
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27 September 2017
Inhibition of cyclin-dependent kinases by p21
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
p21-containing cyclin kinases exist in both active and inactive states
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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27 September 2017
The role of Cdc2 feedback loop control in the DNA damage checkpoint in mammalian cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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30 May 2018
Cyclin E-CDK2 is a regulator of p27Kip1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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30 May 2018
Overexpression of cyclin A but not Skp 2 correlates with the tumor relapse of human hepatocellular carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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28 November 2018
Cell cycle regulation of the p34cdc2/p33cdk2-activating kinase p40MO15.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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28 November 2018
Evidence for a NIMA-like mitotic pathway in vertebrate cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=83921
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28 November 2018
3 Determination of phosphoamino acid composition by acid hydrolysis of protein blotted to immobilon
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/9858587
retrieved
12 December 2020
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Identifiers
DOI
10.1128/MCB.19.1.635
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PMC publication ID
83921
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PubMed publication ID
9858587
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ResearchGate publication ID
13428397
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