(Q24555777)

English

Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells

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Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells (English)

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crystal structure

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protein structure

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1 reference

based on heuristic

inferred from title

membrane protein

1 reference

based on heuristic

inferred from title

author name string

D A Whittington

1

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A Waheed

2

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B Ulmasov

3

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G N Shah

4

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J H Grubb

5

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W S Sly

6

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D W Christianson

7

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language of work or name

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publication date

14 August 2001

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Proceedings of the National Academy of Sciences of the United States of America

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98

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17

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9545-50

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Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system

1 reference

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24 March 2017

Identification of a carbonic anhydrase-like domain in the extracellular region of RPTP gamma defines a new subfamily of receptor tyrosine phosphatases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

A human transmembrane protein-tyrosine-phosphatase, PTP zeta, is expressed in brain and has an N-terminal receptor domain homologous to carbonic anhydrases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Crystal structure of S-glutathiolated carbonic anhydrase III

1 reference

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24 March 2017

A transmembrane helix dimer: structure and implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Crystallographic analysis of Thr-200-->His human carbonic anhydrase II and its complex with the substrate, HCO3-

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structural analysis of the zinc hydroxide-Thr-199-Glu-106 hydrogen-bond network in human carbonic anhydrase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structural basis of inhibitor affinity to variants of human carbonic anhydrase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structure, refinement, and function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Structure of native and apo carbonic anhydrase II and structure of some of its anion-ligand complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Raster3D Version 2.0. A program for photorealistic molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

https://api.crossref.org/works/10.1073/PNAS.161301298

22 April 2017

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Expression of MaTu-MN protein in human tumor cultures and in clinical specimens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

The carbonic anhydrase domain of receptor tyrosine phosphatase beta is a functional ligand for the axonal cell recognition molecule contactin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Human carbonic anhydrases and carbonic anhydrase deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Carbonic anhydrase IV from human lung. Purification, characterization, and comparison with membrane carbonic anhydrase from human kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

24 March 2017

Identification of the von Hippel-Lindau disease tumor suppressor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

7 April 2017

Purification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

Carbonic anhydrase inhibitor suppresses invasion of renal cancer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

The GxxxG motif: a framework for transmembrane helix-helix association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

Expression of the tumor-associated gene MN: a potential biomarker for human renal cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

The catalytic mechanism of carbonic anhydrase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

Carbonic anhydrase II deficiency: diagnosis and carrier detection using differential enzyme inhibition and inactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

27 September 2017

Acidic pH enhances the invasive behavior of human melanoma cells

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27 September 2017

Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant

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27 September 2017

Structural analysis of inhibitor binding to human carbonic anhydrase II

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=55489

30 May 2018

Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination

1 reference

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30 May 2018

Catalysis and inhibition of human carbonic anhydrase IV.

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30 May 2018

The catalytic mechanism of carbonic anhydrase: implications of a rate-limiting protolysis of water

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

AMoRe: an automated package for molecular replacement

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Protein domain interfaces: characterization and comparison with oligomeric protein interfaces

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Statistical analysis of amino acid patterns in transmembrane helices: the GxxxG motif occurs frequently and in association with beta-branched residues at neighboring positions.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Structure of the transmembrane dimer interface of glycophorin A in membrane bilayers

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Discriminating between homodimeric and monomeric proteins in the crystalline state

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28 November 2018

The accessible surface area and stability of oligomeric proteins

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https://api.crossref.org/works/10.1073%2FPNAS.161301298

21 January 2018

Wild-type and E106Q mutant carbonic anhydrase complexed with acetate

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12 December 2020

based on heuristic

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Insights into the function of the zinc hydroxide-Thr199-Glu106 hydrogen bonding network in carbonic anhydrases

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refined structure of the acetazolamide complex of human carbonic anhydrase II at 1.9 A

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of carbonic anhydrase. Subtrate, sulfonamide, and anion binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/11493685

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.161301298

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2001PNAS...98.9545W

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PubMed publication ID

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