(Q24555782)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

title

Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

bilirubin metabolic disorder

9 January 2020

main subject

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

author name string

Viraj P Mane

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Wilma S Norona

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Milton J Finegold

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Philip Ng

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Antony F McDonagh

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Arthur L Beaudet

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

Brendan Lee

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

language of work or name

English

0 references

publication date

7 March 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

9 January 2020

published in

1 reference

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9 January 2020

volume

102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

issue

11

1 reference

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9 January 2020

page(s)

3930-3935

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

Cloning of a human liver microsomal UDP-glucuronosyltransferase cDNA

9 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Distribution and gene expression of cytoskeletal proteins in two-cell rat embryos and developmental arrest

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Congenital jaundice in rats, due to a defect in glucuronide formation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Episomal persistence of recombinant adenoviral vector genomes during the cell cycle in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

A new adenoviral helper-dependent vector results in long-term therapeutic levels of human coagulation factor IX at low doses in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Preparation of helper-dependent adenoviral vectors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Generation of helper-dependent adenoviral vectors by homologous recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

A replication-deficient rSV40 mediates liver-directed gene transfer and a long-term amelioration of jaundice in gunn rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Toxicity associated with repeated administration of first-generation adenovirus vectors does not occur with a helper-dependent vector.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Auxiliary partial orthotopic liver transplantation for Crigler-Najjar syndrome type I.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Toxicological comparison of E2a-deleted and first-generation adenoviral vectors expressing alpha1-antitrypsin after systemic delivery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Tissue-specific, developmental, hormonal, and dietary regulation of rat phosphoenolpyruvate carboxykinase-human growth hormone fusion genes in transgenic mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Long term correction of bilirubin-UDP-glucuronosyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Cerebellar symptoms heralding bilirubin encephalopathy in Crigler-Najjar syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Current therapy for Crigler-Najjar syndrome type 1: report of a world registry.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Genetic defect of bilirubin UDP-glucuronosyltransferase in the hyperbilirubinemic Gunn rat

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

The mechanism of haem catabolism. Bilirubin formation in living rats by [18O]oxygen labelling

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Transplantation of Gunn rats with autologous fibroblasts expressing bilirubin UDP-glucuronosyltransferase: correction of genetic deficiency and tumor formation.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Gene therapy with bilirubin-UDP-glucuronosyltransferase in the Gunn rat model of Crigler-Najjar syndrome type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Long-term reduction of serum bilirubin levels in Gunn rats by retroviral gene transfer in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

A non-immunogenic adenoviral vector, coexpressing CTLA4Ig and bilirubin-uridine-diphosphoglucuronateglucuronosyltransferase permits long-term, repeatable transgene expression in the Gunn rat model of Crigler-Najjar syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

High doses of a helper-dependent adenoviral vector yield supraphysiological levels of alpha1-antitrypsin with negligible toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Hepatobiliary excretion of biliverdin isomers and C10-substituted biliverdins in Mrp2-deficient (TR(-)) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Gene therapy for inherited hyperbilirubinemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Gene therapy. The strange case of chimeraplasty

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Long-term correction of bilirubin UDPglucuronyltransferase deficiency in rats by in utero lentiviral gene transfer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0500930102

Complete correction of hyperbilirubinemia in the Gunn rat model of Crigler-Najjar syndrome type I following transient in vivo adenovirus-mediated expression of human bilirubin UDP-glucuronosyltransferase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=554836

Quantitation of transplanted hepatic mass necessary to cure the Gunn rat model of hyperbilirubinemia

28 November 2018

1 reference

12 December 2020

Characterization and tissue specificity of a monoclonal antibody against human uridine 5'-diphosphate-glucuronosyltransferase

1 reference

12 December 2020

Cytotoxic immune response blunts long-term transgene expression after efficient retroviral-mediated hepatic gene transfer in rat

1 reference

12 December 2020

Helper-dependent adenoviral vectors

1 reference

12 December 2020

Effects of phenobarbital on bilirubin metabolism and its response to phototherapy in the jaundiced Gunn rat

1 reference

12 December 2020

Biochemical and molecular aspects of genetic disorders of bilirubin metabolism

1 reference

12 December 2020

Genetic defects at the UGT1 locus associated with Crigler-Najjar type I disease, including a prenatal diagnosis

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0500930102

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

ADS bibcode

2005PNAS..102.3930T

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15753292%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

2 references