(Q24556563)

English

Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site

scientific article

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scholarly article

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Expression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid site (English)

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author name string

R J Wise

1

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P J Barr

2

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P A Wong

3

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M C Kiefer

4

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A J Brake

5

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R J Kaufman

6

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language of work or name

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publication date

December 1990

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Proceedings of the National Academy of Sciences of the United States of America

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87

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9378-82

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23

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The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma

1 reference

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Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein

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Structural homology between the human fur gene product and the subtilisin-like protease encoded by yeast KEX2

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Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations

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24 March 2017

Protease B of the lysosomelike vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases

1 reference

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24 March 2017

Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease

1 reference

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24 March 2017

Hormone processing and membrane-bound proteinases in yeast

1 reference

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1 reference

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24 March 2017

Yeast KEX2 genes encodes an endopeptidase homologous to subtilisin-like serine proteases

1 reference

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Serine Proteases: Structure and Mechanism of Catalysis

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Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: effects of sequence alterations on efficiency of cleavage

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Post-translational proteolysis in polypeptide hormone biosynthesis

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Identification of a 31,500 molecular weight islet cell protease as cathepsin B

1 reference

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1 reference

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The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors

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Human pituitary tryptase: molecular forms, NH2-terminal sequence, immunocytochemical localization, and specificity with prohormone and fluorogenic substrates.

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Secretion and processing of insulin precursors in yeast

1 reference

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27 September 2017

Nucleotide sequence of pre-pro-von Willebrand factor cDNA.

1 reference

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27 September 2017

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Gene transfer techniques to study neuropeptide processing

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Purification and characterization of a paired basic residue-specific prohormone-converting enzyme from bovine pituitary neural lobe secretory vesicles.

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Intracellular targeting and structural conservation of a prohormone-processing endoprotease.

1 reference

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Amino-terminal sequences of prosomatostatin direct intracellular targeting but not processing specificity

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Identification of a human insulinoma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2.

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The secretion of human serum albumin from the yeast Saccharomyces cerevisiae using five different leader sequences.

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1 reference

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Structure of pre-pro-von Willebrand factor and its expression in heterologous cells

1 reference

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Proalbumin is processed to serum albumin in COS-1 cells transfected with cDNA for rat albumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How signal sequences maintain cleavage specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The propeptide of von Willebrand factor independently mediates the assembly of von Willebrand multimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of synthesis, processing, and secretion of proteins expressed in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propolypeptide of von Willebrand factor circulates in blood and is identical to von Willebrand antigen II

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of preprosomatostatin in heterologous cells: Biosynthesis, posttranslational processing, and secretion of mature somatostatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast KEX2 protease has the properties of a human proalbumin converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/2251280

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.87.23.9378

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1990PNAS...87.9378W

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