(Q24561949)

23 June 2017

The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam (English)

1 reference

23 June 2017

1 reference

Berkley A Lynch

1

Berkley A

Lynch

1 reference

23 June 2017

Nathalie Lambeng

2

Nathalie

Lambeng

1 reference

23 June 2017

Karl Nocka

3

Karl

Nocka

1 reference

23 June 2017

Patricia Kensel-Hammes

4

Patricia

Kensel-Hammes

1 reference

23 June 2017

Sandra M Bajjalieh

5

Sandra M

Bajjalieh

1 reference

23 June 2017

Alain Matagne

6

Alain

Matagne

1 reference

23 June 2017

Bruno Fuks

7

Bruno

Fuks

1 reference

23 June 2017

language of work or name

English

0 references

publication date

21 June 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

23 June 2017

1 reference

23 June 2017

101

1 reference

23 June 2017

9861-9866

1 reference

23 June 2017

26

1 reference

Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)

23 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

A microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brain

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Isoform-specific, calcium-regulated interaction of the synaptic vesicle proteins SV2 and synaptotagmin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

SV2, a brain synaptic vesicle protein homologous to bacterial transporters

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Localization and photoaffinity labelling of the levetiracetam binding site in rat brain and certain cell lines

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Moonlighting proteins: old proteins learning new tricks.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Control of neurotransmitter release by an internal gel matrix in synaptic vesicles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Levetiracetam: a novel antiepileptic drug

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Levetiracetam: the preclinical profile of a new class of antiepileptic drugs?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The evaluation and treatment of seizures

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Differential expression of synaptic vesicle protein 2 (SV2) isoforms.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

The synaptic vesicle protein SV2 is a novel type of transmembrane transporter

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=470764

Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Desynchronizing effect of levetiracetam on epileptiform responses in rat hippocampal slices

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

The novel antiepileptic drug levetiracetam (ucb L059) appears to act via a specific binding site in CNS membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Binding characteristics of [3H]ucb 30889 to levetiracetam binding sites in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

SV2 modulates the size of the readily releasable pool of secretory vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308208101

Phosphorylation of synaptic vesicle protein 2 modulates binding to synaptotagmin

21 January 2018

1 reference

12 December 2020

Evaluation of anticonvulsant drugs in DBA/2 mice with sound-induced seizures

1 reference

12 December 2020

Levetiracetam (ucb LO59) affects in vitro models of epilepsy in CA3 pyramidal neurons without altering normal synaptic transmission

1 reference

12 December 2020

Antiepileptogenic effects of the novel anticonvulsant levetiracetam (ucb L059) in the kindling model of temporal lobe epilepsy

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0308208101

1 reference

release_cennw5qmjndjnaqvq3b22y3qem

23 June 2017

0 references

0 references

OpenCitations bibliographic resource ID

312837

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference