(Q24564569)

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Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat

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Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat (English)

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author name string

D K Wilson

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1

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I Tarle

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2

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J M Petrash

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3

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F A Quiocho

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4

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language of work or name

English

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publication date

1 November 1993

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published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

90

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page(s)

9847-51

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issue

21

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cites work

Novel NADPH-binding domain revealed by the crystal structure of aldose reductase

1 reference

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PubMed Central

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24 March 2017

The crystal structure of the aldose reductase.NADPH binary complex

1 reference

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PubMed Central

reference URL

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24 March 2017

An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications

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PubMed Central

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24 March 2017

Studies on pig muscle aldose reductase. Kinetic mechanism and evidence for a slow conformational change upon coenzyme binding

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24 March 2017

Molecular cloning of testicular 20 alpha-hydroxysteroid dehydrogenase: identity with aldose reductase.

1 reference

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PubMed Central

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retrieved

27 September 2017

Aldose reductase inhibitors: recent developments.

1 reference

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PubMed Central

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27 September 2017

The role of aldose reductase in the development of diabetic complications

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PubMed Central

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retrieved

27 September 2017

Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners

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PubMed Central

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27 September 2017

Involvement of cysteine residues in catalysis and inhibition of human aldose reductase. Site-directed mutagenesis of Cys-80, -298, and -303

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PubMed Central

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retrieved

30 May 2018

Pharmacophor requirements of the aldose reductase inhibitor site

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8234324

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aldose reductase from human psoas muscle. Purification, substrate specificity, immunological characterization, and effect of drugs and inhibitors

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/8234324

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.90.21.9847

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ResearchGate publication ID

14965614

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(Q24564569)

Refined 1.8 A structure of human aldose reductase complexed with the potent inhibitor zopolrestat

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