(Q24598975)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Crystal structure of the Vibrio cholerae cytolysin heptamer reveals common features among disparate pore-forming toxins (English)

1 reference

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29 January 2020

0 references

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Rich Olson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

18 April 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

7385-7390

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

29 January 2020

cites work

1 reference

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Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

24 March 2017

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Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process

24 March 2017

1 reference

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Electrostatics of nanosystems: application to microtubules and the ribosome

24 March 2017

1 reference

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24 March 2017

A short history of SHELX

1 reference

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The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins

24 March 2017

1 reference

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Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore

24 March 2017

1 reference

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Coot: model-building tools for molecular graphics

24 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

The CCP4 suite: programs for protein crystallography

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

UCSF Chimera--a visualization system for exploratory research and analysis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

PHENIX: building new software for automated crystallographic structure determination

24 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

24 March 2017

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

22 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

24 March 2017

https://api.crossref.org/works/10.1073/PNAS.1017442108

Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Lipid rafts as a membrane-organizing principle

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Only two amino acids are essential for cytolytic toxin recognition of cholesterol at the membrane surface

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Three-dimensional structure of the anthrax toxin pore inserted into lipid nanodiscs and lipid vesicles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Successful small intestine colonization of adult mice by Vibrio cholerae requires ketamine anesthesia and accessory toxins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Phenylalanine-427 of anthrax protective antigen functions in both pore formation and protein translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Pore formation: an ancient yet complex form of attack.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Anthrax toxin: receptor binding, internalization, pore formation, and translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

A loop network within the anthrax toxin pore positions the phenylalanine clamp in an active conformation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

A rivet model for channel formation by aerolysin-like pore-forming toxins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

A molecular model of the Vibrio cholerae cytolysin transmembrane pore

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Role of the amino latch of staphylococcal alpha-hemolysin in pore formation: a co-operative interaction between the N terminus and position 217.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Interactions of peptides with a protein pore

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

High resolution crystallographic studies of alpha-hemolysin-phospholipid complexes define heptamer-lipid head group interactions: implication for understanding protein-lipid interactions.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Vibrio cholerae cytolysin is composed of an alpha-hemolysin-like core

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Not as simple as just punching a hole

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Plasma membrane microdomains act as concentration platforms to facilitate intoxication by aerolysin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Potent membrane-permeabilizing and cytocidal action of Vibrio cholerae cytolysin on human intestinal cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

In vitro proteolytic processing and activation of the recombinant precursor of El Tor cytolysin/hemolysin (pro-HlyA) of Vibrio cholerae by soluble hemagglutinin/protease of V. cholerae, trypsin, and other proteases.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Mechanism of membrane damage by El Tor hemolysin of Vibrio cholerae O1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Interactions between residues in staphylococcal alpha-hemolysin revealed by reversion mutagenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

The pore dimensions of gramicidin A.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

The aromatic ring of phenylalanine 334 is essential for oligomerization of Vibrio vulnificus hemolysin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Pro-inflammatory feedback activation cycle evoked by attack of Vibrio cholerae cytolysin on human neutrophil granulocytes

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Oligomerization of Vibrio cholerae cytolysin yields a pentameric pore and has a dual specificity for cholesterol and sphingolipids in the target membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Crystal structure of the Vibrio cholerae cytolysin (VCC) pro-toxin and its assembly into a heptameric transmembrane pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Prepore for a breakthrough

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Three-dimensional structure of the detergent-solubilized Vibrio cholerae cytolysin (VCC) heptamer by electron cryomicroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Interaction of the Vibrio cholerae cytolysin (VCC) with cholesterol, some cholesterol esters, and cholesterol derivatives: a TEM study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

A phenylalanine clamp catalyzes protein translocation through the anthrax toxin pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Ion channels of biological membranes: prediction of single channel conductance

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1017442108

Pore formation by Vibrio cholerae cytolysin requires cholesterol in both monolayers of the target membrane

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Staphylococcal alpha-toxin: formation of the heptameric pore is partially cooperative and proceeds through multiple intermediate stages

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088620

Assembly of the oligomeric membrane pore formed by Staphylococcal alpha-hemolysin examined by truncation mutagenesis

28 November 2018

1 reference

12 December 2020

HlyA hemolysin of Vibrio cholerae O1 biotype E1 Tor. Identification of the hemolytic complex and evidence for the formation of anion-selective ion-permeable channels

1 reference

12 December 2020

Carbohydrate-mediated regulation of interaction of Vibrio cholerae hemolysin with erythrocyte and phospholipid vesicle

1 reference

12 December 2020

An intermediate in the assembly of a pore-forming protein trapped with a genetically-engineered switch

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1017442108

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

ADS bibcode

2011PNAS..108.7385D

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21502531%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

21502531

2 references