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Transposon-based screens for cancer gene discovery in mouse models
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scholarly article
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review article
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Europe PubMed Central
title
Transposon-based screens for cancer gene discovery in mouse models
(English)
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author name string
Adam J Dupuy
series ordinal
1
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language of work or name
English
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publication date
August 2010
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published in
Seminars in Cancer Biology
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volume
20
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page(s)
261-8
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issue
4
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cites work
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7 April 2017
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7 April 2017
Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates
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7 April 2017
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Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells
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Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality
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A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice
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Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras
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The NemaGENETAG initiative: large scale transposon insertion gene-tagging in Caenorhabditis elegans
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A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.
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Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks
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27 September 2017
Transposon-mediated mutagenesis in somatic cells: identification of transposon-genomic DNA junctions
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27 September 2017
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27 September 2017
SOME POSSIBLE EFFECTS OF NURSING ON THE MAMMARY GLAND TUMOR INCIDENCE IN MICE.
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27 September 2017
MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.
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27 September 2017
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27 September 2017
Hyperactive transposase mutants of the Sleeping Beauty transposon
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27 September 2017
Gene transfer into genomes of human cells by the sleeping beauty transposon system.
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27 September 2017
Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon
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27 September 2017
Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition
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27 September 2017
Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.
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27 September 2017
Transposition and gene disruption in the male germline of the mouse
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27 September 2017
Insertional mutagenesis of the Drosophila genome with single P elements
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27 September 2017
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
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reference URL
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30 May 2018
DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.
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30 May 2018
Chromosomal mobilization and reintegration of Sleeping Beauty and PiggyBac transposons.
1 reference
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PubMed Central
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28 November 2018
Parallel progression of primary tumours and metastases
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28 November 2018
Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2940989
retrieved
28 November 2018
Identifiers
DOI
10.1016/J.SEMCANCER.2010.05.003
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PMCID
2940989
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PubMed ID
20478384
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ResearchGate publication ID
44607429
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