(Q24610496)

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Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)

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Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics) (English)

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author name string

Tomoaki Uchiki

1

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Karen A Weikel

2

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Wangwang Jiao

3

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Fu Shang

4

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Andrea Caceres

5

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Dorota Pawlak

6

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James T Handa

7

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Michael Brownlee

8

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Ram Nagaraj

9

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Allen Taylor

10

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language of work or name

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publication date

February 2012

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11

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1

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1-13

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Informing food choices and health outcomes by use of the dietary glycemic index

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Misfolded proteins partition between two distinct quality control compartments

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

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The roles of intracellular protein-degradation pathways in neurodegeneration

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7 April 2017

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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

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7 April 2017

Impairment of the ubiquitin-proteasome system by protein aggregation

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7 April 2017

Ubiquitin-proteasome pathway and cellular responses to oxidative stress

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27 September 2017

Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions

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27 September 2017

Methylglyoxal alters the function and stability of critical components of the protein quality control

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27 September 2017

Dietary hyperglycemia, glycemic index and metabolic retinal diseases

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27 September 2017

Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis

1 reference

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27 September 2017

Protein homeostasis and aging: The importance of exquisite quality control

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Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.

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27 September 2017

Molecular mechanisms of proteasome plasticity in aging

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27 September 2017

Ageing, neurodegeneration and Parkinson's disease

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27 September 2017

Identifying advanced glycation end products as a major source of oxidants in aging: implications for the management and/or prevention of reduced renal function in elderly persons

1 reference

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27 September 2017

Highlights and hotspots of protein glycation in end-stage renal disease

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27 September 2017

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

1 reference

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D-Ribosylated Tau forms globular aggregates with high cytotoxicity

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27 September 2017

The role of advanced glycation end products in retinal ageing and disease.

1 reference

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Stress-induced premature senescence of endothelial cells: a perilous state between recovery and point of no return

1 reference

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27 September 2017

Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Rapid glycation with D-ribose induces globular amyloid-like aggregations of BSA with high cytotoxicity to SH-SY5Y cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Selective accumulation of aggregation-prone proteasome substrates in response to proteotoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Long-term effects of dietary glycemic index on adiposity, energy metabolism, and physical activity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Advanced glycation end product (AGE) accumulation on Bruch's membrane: links to age-related RPE dysfunction

1 reference

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27 September 2017

Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related diseases, and lifespan

1 reference

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27 September 2017

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1 reference

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27 September 2017

Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Degradation of C-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway.

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27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Association between dietary glycemic index and age-related macular degeneration in nondiabetic participants in the Age-Related Eye Disease Study

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

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27 September 2017

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27 September 2017

Macular degeneration: recent advances and therapeutic opportunities.

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27 September 2017

Glutathiolation enhances the degradation of gammaC-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway

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27 September 2017

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27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: a comprehensive transcriptional response

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

The maillard reaction in eye diseases

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27 September 2017

Lys6-modified ubiquitin inhibits ubiquitin-dependent protein degradation.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Roles of the receptor for advanced glycation endproducts in diabetes-induced vascular injury

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27 September 2017

Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity

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27 September 2017

Glycemic index in chronic disease: a review

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Drusen proteome analysis: an approach to the etiology of age-related macular degeneration.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

Retinal pigment epithelial cell distribution in central retina of rhesus monkeys.

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27 September 2017

Glycemic index: overview of implications in health and disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

The glycemic index: physiological mechanisms relating to obesity, diabetes, and cardiovascular disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

27 September 2017

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27 September 2017

Advanced glycated albumin impairs protein degradation in the kidney proximal tubules cell line LLC-PK1.

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27 September 2017

Advanced glycation end products in Alzheimer's disease and other neurodegenerative diseases

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27 September 2017

Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women

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27 September 2017

Accumulation of pyrraline-modified albumin in phagocytes due to reduced degradation by lysosomal enzymes

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27 September 2017

The ubiquitin pathway for the degradation of intracellular proteins

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27 September 2017

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30 May 2018

Quantitative screening of advanced glycation endproducts in cellular and extracellular proteins by tandem mass spectrometry

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30 May 2018

Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells.

1 reference

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30 May 2018

Development of a polyclonal antibody with broad epitope specificity for advanced glycation endproducts and localization of these epitopes in Bruch's membrane of the aging eye.

1 reference

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30 May 2018

Increase in the advanced glycation end product pentosidine in Bruch's membrane with age.

1 reference

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30 May 2018

Advanced glycation end products in age-related macular degeneration

1 reference

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30 May 2018

Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells

1 reference

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30 May 2018

Fructated Protein Is More Resistant to ATP-Dependent Proteolysis than Glucated Protein Possibly as a Result of Higher Content of Maillard Fluorophores

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30 May 2018

Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins

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21 January 2018

Depletion of 26S proteasomes in mouse brain neurons causes neurodegeneration and Lewy-like inclusions resembling human pale bodies.

1 reference

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21 January 2018

Proteasome inhibition in glyoxal-treated fibroblasts and resistance of glycated glucose-6-phosphate dehydrogenase to 20 S proteasome degradation in vitro.

1 reference

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21 January 2018

A photoconvertible reporter of the ubiquitin-proteasome system in vivo

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21 January 2018

Metabolic effects of diets differing in glycaemic index depend on age and endogenous glucose-dependent insulinotrophic polypeptide in mice.

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21 January 2018

A transgenic mouse model of the ubiquitin/proteasome system

1 reference

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21 January 2018

Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions

1 reference

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21 January 2018

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans

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21 January 2018

Cumulative glycemia and microangiopathy in subjects with impaired glucose regulation in the Inter99 study.

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21 January 2018

Effects of dietary glycaemic index on adiposity, glucose homoeostasis, and plasma lipids in animals.

1 reference

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21 January 2018

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation

1 reference

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21 January 2018

Ubiquitination capabilities in response to neocarzinostatin and H(2)O(2) stress in cell lines from patients with ataxia-telangiectasia

1 reference

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21 January 2018

Structure and mechanism of formation of human lens fluorophore LM-1. Relationship to vesperlysine A and the advanced Maillard reaction in aging, diabetes, and cataractogenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00752.X

21 January 2018

Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process

1 reference

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21 January 2018

Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice.

1 reference

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21 January 2018

Dietary carbohydrate and the progression of age-related macular degeneration: a prospective study from the Age-Related Eye Disease Study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3257376

28 November 2018

Ubiquitin and ubiquitin conjugates in human lens

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ubiquitin: new insights into chronic degenerative diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of proteasome and calpain inhibitors on the structural reorganization and proliferation of vascular smooth muscle cells in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of nonenzymatic glycation on ubiquitination and ubiquitin-mediated degradation of lysozyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of ubiquitin-conjugating enzymes by glutathione following oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/21967227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1474-9726.2011.00752.X

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