(Q24616751)

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Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics

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scholarly article

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Europe PubMed Central

Drug delivery trends in clinical trials and translational medicine: challenges and opportunities in the delivery of nucleic acid-based therapeutics (English)

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based on heuristic

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translational medicine

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based on heuristic

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author name string

Long Xu

1

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Thomas Anchordoquy

2

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language of work or name

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publication date

January 2011

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Journal of Pharmaceutical Sciences

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100

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1

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38-52

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7 April 2017

Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease

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Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

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7 April 2017

Effect of cholesterol nanodomains on the targeting of lipid-based gene delivery in cultured cells

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Rexin-G, a targeted genetic medicine for cancer

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

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27 September 2017

Biological barriers to therapy with antisense and siRNA oligonucleotides

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27 September 2017

Engineered nanoscaled polyplex gene delivery systems

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Synthesis and biological evaluation of a bioresponsive and endosomolytic siRNA-polymer conjugate.

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Mediating tumor targeting efficiency of nanoparticles through design

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27 September 2017

A novel mechanism is involved in cationic lipid-mediated functional siRNA delivery

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27 September 2017

Nonviral methods for siRNA delivery

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27 September 2017

Targeted delivery of siRNA by nonviral vectors: lessons learned from recent advances.

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27 September 2017

Pharmacokinetics and biodistribution of nanoparticles

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27 September 2017

Cholesterol domains in cationic lipid/DNA complexes improve transfection

1 reference

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27 September 2017

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.

1 reference

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

1 reference

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27 September 2017

Delivery vehicles for small interfering RNA in vivo

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Overcoming the innate immune response to small interfering RNA.

1 reference

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27 September 2017

Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes

1 reference

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Efficient gene silencing in metastatic tumor by siRNA formulated in surface-modified nanoparticles

1 reference

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27 September 2017

Effect of structural relaxation on the preparation and drug release behavior of poly(lactic-co-glycolic)acid microparticle drug delivery systems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

In vivo comparative study of lipid/DNA complexes with different in vitro serum stability: effects on biodistribution and tumor accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Dynamic PolyConjugates for targeted in vivo delivery of siRNA to hepatocytes

1 reference

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1 reference

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27 September 2017

Cationic lipid complexed camptothecin (EndoTAG-2) improves antitumoral efficacy by tumor vascular targeting

1 reference

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27 September 2017

Systemic siRNA delivery via hydrodynamic intravascular injection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Structure and gene silencing activities of monovalent and pentavalent cationic lipid vectors complexed with siRNA.

1 reference

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27 September 2017

Lipid encapsulation enables the effective systemic delivery of polyplex plasmid DNA.

1 reference

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1 reference

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27 September 2017

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1 reference

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27 September 2017

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1 reference

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27 September 2017

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1 reference

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27 September 2017

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1 reference

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27 September 2017

Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA.

1 reference

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27 September 2017

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1 reference

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27 September 2017

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27 September 2017

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27 September 2017

Cationic liposomes as in vivo delivery vehicles

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

The promise of nucleic acid vaccines

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27 September 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Stabilized plasmid-lipid particles: construction and characterization

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27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

DNA condensation for gene therapy as monitored by atomic force microscopy

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Effect of serum components on the physico-chemical properties of cationic lipid/oligonucleotide complexes and on their interactions with cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Characterization of liposome-mediated gene delivery: expression, stability and pharmacokinetics of plasmid DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake

1 reference

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27 September 2017

An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

27 September 2017

A Transition to a Compact Form of DNA in Polymer Solutions

1 reference

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27 September 2017

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors

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27 September 2017

Cationic liposome-mediated RNA transfection

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27 September 2017

Serum opsonins and liposomes: their interaction and opsonophagocytosis

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27 September 2017

Expression of naked plasmids by cultured myotubes and entry of plasmids into T tubules and caveolae of mammalian skeletal muscle

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27 September 2017

The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.

1 reference

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30 May 2018

Influence of poly(ethylene glycol) grafting density and polymer length on liposomes: relating plasma circulation lifetimes to protein binding.

1 reference

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30 May 2018

Low molecular weight dextrans stabilize nonviral vectors during lyophilization at low osmolalities: concentrating suspensions by rehydration to reduced volumes

1 reference

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30 May 2018

A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

30 May 2018

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

1 reference

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30 May 2018

Stabilized plasmid-lipid particles for systemic gene therapy

1 reference

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30 May 2018

A phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme.

1 reference

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30 May 2018

DNA toroids: stages in condensation

1 reference

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30 May 2018

Optimization of cell surface binding enhances efficiency and specificity of molecular conjugate gene delivery

1 reference

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30 May 2018

Overcoming the inhibitory effect of serum on lipofection by increasing the charge ratio of cationic liposome to DNA.

1 reference

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30 May 2018

Polymer-protein interactions. Comparison of experiment and excluded volume theory.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

30 May 2018

Liposome-mediated delivery of deoxyribonucleic acid to cells: enhanced efficiency of delivery by changes in lipid composition and incubation conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

30 May 2018

Introduction of liposome-encapsulated SV40 DNA into cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

30 May 2018

The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

30 May 2018

Condensation of DNA by multivalent cations: Considerations on mechanism

1 reference

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30 May 2018

Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes

1 reference

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30 May 2018

A compact form of double-stranded DNA in solution

1 reference

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30 May 2018

Gene therapy deserves a fresh chance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Vascular targeting by EndoTAG-1 enhances therapeutic efficacy of conventional chemotherapy in lung and pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Formulation development of freeze-dried oligonucleotide-loaded gelatin nanoparticles

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28 November 2018

Converging paths of viral and non-viral vector engineering

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28 November 2018

Non-viral is superior to viral gene delivery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Comparison of gene expression efficiency and innate immune response induced by Ad vector and lipoplex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

RNAi-mediated gene silencing in non-human primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

China approves world's first oncolytic virus therapy for cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Design of noninflammatory synthetic siRNA mediating potent gene silencing in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Hydrolytic degradation of poly(ethylene oxide)-block-polycaprolactone worm micelles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Immunogenicity and rapid blood clearance of liposomes containing polyethylene glycol-lipid conjugates and nucleic Acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Macrophage activation by a DNA/cationic liposome complex requires endosomal acidification and TLR9-dependent and -independent pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Non-immunostimulatory nonviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

The role of lipid charge density in the serum stability of cationic lipid/DNA complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Steric stabilization of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG-lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Systemic tumor-targeted gene delivery by anti-transferrin receptor scFv-immunoliposomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Effects of PEGylation on the preservation of cationic lipid/DNA complexes during freeze-thawing and lyophilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Modification of pLL/DNA complexes with a multivalent hydrophilic polymer permits folate-mediated targeting in vitro and prolonged plasma circulation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

The role of tissue macrophages in the induction of proinflammatory cytokine production following intravenous injection of lipoplexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Liposome clearance in mice: the effect of a separate and combined presence of surface charge and polymer coating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Stabilized plasmid-lipid particles: a systemic gene therapy vector

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Prevention of antibody-mediated elimination of ligand-targeted liposomes by using poly(ethylene glycol)-modified lipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Factors affecting the accelerated blood clearance of polyethylene glycol-liposomes upon repeated injection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Surface-associated serum proteins inhibit the uptake of phosphatidylserine and poly(ethylene glycol) liposomes by mouse macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Interaction between DNA-cationic liposome complexes and erythrocytes is an important factor in systemic gene transfer via the intravenous route in mice: the role of the neutral helper lipid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Selective protein interactions with phosphatidylserine containing liposomes alter the steric stabilization properties of poly(ethylene glycol).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Gene-therapy death prompts broad civil lawsuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Efficient encapsulation of DNA plasmids in small neutral liposomes induced by ethanol and calcium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Repeat administration of DNA/liposomes to the nasal epithelium of patients with cystic fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Stabilized plasmid-lipid particles: pharmacokinetics and plasmid delivery to distal tumors following intravenous injection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Accelerated blood clearance and altered biodistribution of repeated injections of sterically stabilized liposomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Time-dependent maturation of cationic liposome-DNA complex for serum resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Inclusion of cholesterol in DOTAP transfection complexes increases the delivery of DNA to cells in vitro in the presence of serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

Serum opsonins and phagocytosis of saturated and unsaturated phospholipid liposomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3303188

28 November 2018

EndoTAG-1. MediGene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Receptor versus non-receptor mediated clearance of liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Micelles from polyethylene glycol/phosphatidylethanolamine conjugates for tumor drug delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amphiphilic vinyl polymers effectively prolong liposome circulation time in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of poly(ethylene glycol)-lipid conjugates to regulate the surface attributes and transfection activity of lipid-DNA particles

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PEG grafting of polyethylenimine (PEI) exerts different effects on DNA transfection and siRNA-induced gene targeting efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of plasmid delivery by hydrodynamic tail vein injection. I. Hepatocyte uptake of various molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

32 Liposomes as carriers for intracellular delivery of nucleic acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coating particles with a block co-polymer (poloxamine-908) suppresses opsonization but permits the activity of dysopsonins in the serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of different hydrophobic anchors conjugated to poly(ethylene glycol): effects on the pharmacokinetics of liposomal vincristine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homing in on delivery

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid-DNA complexes induce potent activation of innate immune responses and antitumor activity when administered intravenously

1 reference

https://pubmed.ncbi.nlm.nih.gov/20575003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JPS.22243

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Sitelinks

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