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Pain as a channelopathy
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Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
title
Pain as a channelopathy
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author
Ramin Raouf
series ordinal
1
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Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
author name string
Kathryn Quick
series ordinal
2
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Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
John N Wood
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3
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Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
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15 January 2020
language of work or name
English
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publication date
1 November 2010
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Europe PubMed Central
PMCID
2965577
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retrieved
15 January 2020
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
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15 January 2020
volume
120
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
page(s)
3745-3752
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Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
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Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neurons
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Pain channelopathies
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Transient receptor potential channelopathies
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Sodium channelopathies and pain
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A neural mechanism for exacerbation of headache by light
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Scapuloperoneal spinal muscular atrophy and CMT2C are allelic disorders caused by alterations in TRPV4.
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27 September 2017
A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome
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27 September 2017
Alternative splicing of Na(V)1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T.
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27 September 2017
Origin of pain in migraine: evidence for peripheral sensitisation
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27 September 2017
Molecular genetics of migraine
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27 September 2017
TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization
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27 September 2017
Neuropathic pain: a maladaptive response of the nervous system to damage
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27 September 2017
Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations.
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27 September 2017
Animal models of pain: progress and challenges
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27 September 2017
Genetic calcium signaling abnormalities in the central nervous system: seizures, migraine, and autism
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27 September 2017
Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1.
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PubMed Central
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27 September 2017
Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy
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27 September 2017
Inherited neuronal ion channelopathies: new windows on complex neurological diseases
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27 September 2017
Sensory neuron voltage-gated sodium channels as analgesic drug targets
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27 September 2017
Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves
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27 September 2017
Genetics of irritable bowel syndrome
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27 September 2017
Self-limited hyperexcitability: functional effect of a familial hemiplegic migraine mutation of the Nav1.1 (SCN1A) Na+ channel
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27 September 2017
Divergent sodium channel defects in familial hemiplegic migraine
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27 September 2017
Neuronal TRP channels: thermometers, pathfinders and life-savers
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27 September 2017
Mutations in sodium-channel gene SCN9A cause a spectrum of human genetic pain disorders
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27 September 2017
The roles of sodium channels in nociception: Implications for mechanisms of pain
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Sodium channel expression and the molecular pathophysiology of pain after SCI.
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27 September 2017
The Pain Genes Database: An interactive web browser of pain-related transgenic knockout studies
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27 September 2017
Migraine: a complex genetic disorder
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Functional biology of the alpha(2)delta subunits of voltage-gated calcium channels
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Ca2+ channel alpha2delta ligands: novel modulators of neurotransmission
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PubMed Central
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27 September 2017
Identification of the alpha2-delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Erythermalgia: molecular basis for an inherited pain syndrome
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Autosomal dominant erythermalgia associated with a novel mutation in the voltage-gated sodium channel alpha subunit Nav1.7.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Electrophysiological properties of mutant Nav1.7 sodium channels in a painful inherited neuropathy.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
Voltage-gated sodium channels and pain pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
The primary erythermalgia-susceptibility gene is located on chromosome 2q31-32.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
Potent analgesic effects of GDNF in neuropathic pain states.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
NK1 (substance P) receptor antagonists--why are they not analgesic in humans?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
27 September 2017
Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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27 September 2017
Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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30 May 2018
Sodium channels gone wild: resurgent current from neuronal and muscle channelopathies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
30 May 2018
Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
30 May 2018
Enhanced excitatory transmission at cortical synapses as the basis for facilitated spreading depression in Ca(v)2.1 knockin migraine mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
First mutation in the voltage-gated Nav1.1 subunit gene SCN1A with co-occurring familial hemiplegic migraine and epilepsy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
The Cell and Molecular Basis of Mechanical, Cold, and Inflammatory Pain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Na,K-ATPase and the role of alpha isoforms in behavior
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
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28 November 2018
The novel p.L1649Q mutation in the SCN1A epilepsy gene is associated with familial hemiplegic migraine: genetic and functional studies. Mutation in brief #957. Online.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Gastrointestinal symptoms in families of patients with an SCN5A-encoded cardiac channelopathy: evidence of an intestinal channelopathy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Comparative activity of the anti-convulsants oxcarbazepine, carbamazepine, lamotrigine and gabapentin in a model of neuropathic pain in the rat and guinea-pig
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Sodium current in human intestinal interstitial cells of Cajal
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
The tetrodotoxin-resistant Na+ channel Nav1.8 is essential for the expression of spontaneous activity in damaged sensory axons of mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Impaired Pressure Sensation in Mice Lacking TRPV4
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Intrinsic brain activity triggers trigeminal meningeal afferents in a migraine model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
A role for the TTX-resistant sodium channel Nav 1.8 in NGF-induced hyperalgesia, but not neuropathic pain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Focal hyperemia followed by spreading oligemia and impaired activation of rcbf in classic migraine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2965577
retrieved
28 November 2018
Erythromelalgia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21041956
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Differential Spinal Cord Gene Expression in Rodent Models of Radicular and Neuropathic Pain
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21041956
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI43158
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PMCID
2965577
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
PubMed ID
21041956
1 reference
stated in
Europe PubMed Central
PMCID
2965577
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21041956%20AND%20SRC:MED&resulttype=core&format=json
retrieved
15 January 2020
ResearchGate publication ID
47645208
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