(Q24634206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

0 references

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Wolf-Dieter Schubert

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Gunhild Layer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Jürgen Moser

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

Dirk W Heinz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

language of work or name

English

0 references

publication date

1 December 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

6214-6224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

21 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Crystal structure of human uroporphyrinogen decarboxylase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Structure and mechanism of the glycyl radical enzyme pyruvate formate-lyase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Refinement of macromolecular structures by the maximum-likelihood method

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Automated refinement of protein models

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

The CCP4 suite: programs for protein crystallography

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Improved methods for building protein models in electron density maps and the location of errors in these models

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Oxygen-independent coproporphyrinogen-III oxidase HemN from Escherichia coli

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Many paths to methyltransfer: a chronicle of convergence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Miscellaneous algorithms for density modification

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

S-Adenosylmethionine: a wolf in sheep's clothing, or a rich man's adenosylcobalamin?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

The generation of 5′-deoxyadenosyl radicals by adenosylmethionine-dependent radical enzymes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Terminal steps of haem biosynthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Adenosylmethionine as a source of 5'-deoxyadenosyl radicals

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Adenosylmethionine-dependent iron-sulfur enzymes: versatile clusters in a radical new role

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Control of adenosylmethionine-dependent radical generation in biotin synthase: a kinetic and thermodynamic analysis of substrate binding to active and inactive forms of BioB.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Universal catalytic domain structure of AdoMet-dependent methyltransferases.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Anaerobic and aerobic coproporphyrinogen III oxidases of Rhodopseudomonas spheroides. Mechanism and stereochemistry of vinyl group formation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Chromatographic analysis of the chiral and covalent instability of S-adenosyl-L-methionine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

Direct H atom abstraction from spore photoproduct C-6 initiates DNA repair in the reaction catalyzed by spore photoproduct lyase: evidence for a reversibly generated adenosyl radical intermediate

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=291839

A Glycyl Radical Site in the Crystal Structure of a Class III Ribonucleotide Reductase

28 November 2018

1 reference

12 December 2020

Direct FeS cluster involvement in generation of a radical in lysine 2,3-aminomutase

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

1 reference

12 December 2020

Chiral instability at sulfur of S-adenosylmethionine

1 reference

12 December 2020

Determination of the absolute configuration at the sulfonium center of S-adenosylmethionine. Correlation with the absolute configuration of the diastereomeric S-carboxymethyl-(S)-methionine salts

1 reference

12 December 2020

Membrane glycoprotein folding, oligomerization and intracellular transport: effects of dithiothreitol in living cells.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

An antagonist-insensitive P2X receptor expressed in epithelia and brain

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Analysis of molecular masses and oligomeric states of protein complexes by blue native electrophoresis and isolation of membrane protein complexes by two-dimensional native electrophoresis

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Structural motif and characteristics of the extracellular domain of P2X receptors

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Molecular assembly of the extracellular domain of P2X2, an ATP-gated ion channel

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

P2-purinoceptor antagonists: I. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by small aromatic isothiocyanato-sulphonates

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

PPADS, a novel functionally selective antagonist of P2 purinoceptor-mediated responses

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The use of a new series of cleavable protein-crosslinkers on the Escherichia coli ribosome.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Purinoceptors: are there families of P2X and P2Y purinoceptors?

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Bivalent ligands and the message-address concept in the design of selective opioid receptor antagonists

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Evolutionary history of the ligand-gated ion-channel superfamily of receptors

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

A vector for the synthesis of cRNAs encoding Myc epitope-tagged proteins in Xenopus laevis oocytes.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Ligand-gated ion channels in the brain: the amino acid receptor superfamily

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Determination of the subunit stoichiometry of an inwardly rectifying potassium channel

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Quality control in the secretory pathway

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Structure and function of glutamate and nicotinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Dimensions of the narrow portion of a recombinant NMDA receptor channel

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Estimation of the pore size of the large-conductance mechanosensitive ion channel of Escherichia coli.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Structure of the NMDA receptor channel M2 segment inferred from the accessibility of substituted cysteines.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Families of ion channels with two hydrophobic segments

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Purinergic receptors: their role in nociception and primary afferent neurotransmission

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Structure of gap junction intercellular channels

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Protein folds in channel structure

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Selective radiolabeling of cell surface proteins to a high specific activity

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Acetylcholine receptor channel imaged in the open state

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

A P2X purinoceptor expressed by a subset of sensory neurons

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Cloning of the amiloride-sensitive FMRFamide peptide-gated sodium channel.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Evidence for intracellular sodium pumps in permeabilized Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Quaternary structure of the native GABAA receptor determined by electron microscopic image analysis.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Ultrastructure of the 5-hydroxytryptamine3 receptor.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Pentameric subunit stoichiometry of a neuronal glutamate receptor

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Fixation of allosteric states of the nicotinic acetylcholine receptor by chemical cross-linking

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Isoform-specific interactions of Na,K-ATPase subunits are mediated via extracellular domains and carbohydrates

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The permeabilizing ATP receptor, P2X7. Cloning and expression of a human cDNA

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Electrophysiological and biochemical evidence that DEG/ENaC cation channels are composed of nine subunits

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Assembly of influenza hemagglutinin trimers and its role in intracellular transport

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Posttranslational oligomerization and cooperative acid activation of mixed influenza hemagglutinin trimers

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The permeability of the endplate channel to organic cations in frog muscle

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Identification of amino acid residues contributing to the pore of a P2X receptor

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The heterotetrameric architecture of the epithelial sodium channel (ENaC).

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

A tetrameric subunit stoichiometry for a glutamate receptor-channel complex.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Primary structure and functional expression of the alpha-, beta-, gamma-, delta- and epsilon-subunits of the acetylcholine receptor from rat muscle

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The emerging three-dimensional structure of a receptor. The nicotinic acetylcholine receptor

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

P2X receptors: an emerging channel family

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Development and perspectives of the purinoceptor concept

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Design and pharmacology of selective P2-purinoceptor antagonists

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Dimensions and ion selectivity of recombinant AMPA and kainate receptor channels and their dependence on Q/R site residues

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Characterization of recombinant human P2X4 receptor reveals pharmacological differences to the rat homologue

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Identification of synaptophysin as a hexameric channel protein of the synaptic vesicle membrane

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Cloned glutamate receptors

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Disulfide-linked aggregation of thyroglobulin normally occurs during nascent protein folding

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Evidence for a tetrameric structure of recombinant NMDA receptors.

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2FCDG598

7 January 2021

Identifiers

DOI

10.1093/EMBOJ/CDG598

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14633981%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference