(Q24642217)

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Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice

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scholarly article

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Kv1.3 gene-targeted deletion alters longevity and reduces adiposity by increasing locomotion and metabolism in melanocortin-4 receptor-null mice (English)

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human nutrition

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author name string

K Tucker

1

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J M Overton

2

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D A Fadool

3

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language of work or name

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publication date

August 2008

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International Journal of Obesity

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32

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8

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1222-32

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The melanocortin system and energy balance

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The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity

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7 April 2017

Two adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase

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7 April 2017

A novel potassium channel in lymphocyte mitochondria

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7 April 2017

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

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7 April 2017

The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight

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7 April 2017

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22 April 2017

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

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7 April 2017

Extended longevity in mice lacking the insulin receptor in adipose tissue

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7 April 2017

Deletion of voltage-gated channel affects glomerular refinement and odorant receptor expression in the mouse olfactory system

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27 September 2017

Central neural and endocrine mechanisms of non-exercise activity thermogenesis and their potential impact on obesity

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27 September 2017

Post-synaptic density perturbs insulin-induced Kv1.3 channel modulation via a clustering mechanism involving the SH3 domain

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27 September 2017

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27 September 2017

The action potential in mammalian central neurons

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27 September 2017

Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene

1 reference

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27 September 2017

Brainstem mechanisms integrating gut-derived satiety signals and descending forebrain information in the control of meal size

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27 September 2017

Non-conducting functions of voltage-gated ion channels

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27 September 2017

Modulation of appetite by gonadal steroid hormones

1 reference

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27 September 2017

Some mathematical and technical issues in the measurement and interpretation of open-circuit indirect calorimetry in small animals

1 reference

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27 September 2017

Mouse models of obesity

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27 September 2017

New methods for calculating metabolic rate with special reference to protein metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Kv1.3 channel gene-targeted deletion produces "Super-Smeller Mice" with altered glomeruli, interacting scaffolding proteins, and biophysics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Neurotrophin modulation of voltage-gated potassium channels in rat through TrkB receptors is time and sensory experience dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

A metabolic defect promotes obesity in mice lacking melanocortin-4 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Suppression of the rat microglia Kv1.3 current by src-family tyrosine kinases and oxygen/glucose deprivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Brain insulin receptor causes activity-dependent current suppression in the olfactory bulb through multiple phosphorylation of Kv1.3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

BDNF regulates eating behavior and locomotor activity in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Distribution in rat brain of binding sites of kaliotoxin, a blocker of Kv1.1 and Kv1.3 alpha-subunits.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Modulation of the Kv1.3 potassium channel by receptor tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Effects of food restriction on aging: separation of food intake and adiposity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Voltage-dependent ion channels in T-lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

27 September 2017

Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus increases energy expenditure by elevating metabolic rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

30 May 2018

Voltage-gated potassium channel Kv1.3 regulates GLUT4 trafficking to the plasma membrane via a Ca2+-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

30 May 2018

Concurrent reductions in blood pressure and metabolic rate during fasting in the unrestrained SHR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737548

30 May 2018

Heterogeneous Expression Patterns of Mammalian Potassium Channel Genes in Developing and Adult Rat Brain.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Divergence of melanocortin pathways in the control of food intake and energy expenditure

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Daily cycles in body temperature, metabolic rate, and substrate utilization in pigeons: influence of amount and timing of food consumption.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Cardiovascular responses to caloric restriction and thermoneutrality in C57BL/6J mice.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Brain stem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Compulsive exercise acutely upregulates rat hippocampal brain-derived neurotrophic factor

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reduces energy intake

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Brain-derived neurotrophic factor in the ventromedial nucleus of the hypothalamus reduces energy intake

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Brain-derived neurotrophic factor enhances glucose utilization in peripheral tissues of diabetic mice

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

A mechanism underlying mature-onset obesity: evidence from the hyperphagic phenotype of brain-derived neurotrophic factor mutants

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive".

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Melanocortin-4 Receptor Activation Stimulates Hypothalamic Brain-Derived Neurotrophic Factor Release to Regulate Food Intake, Body Temperature and Cardiovascular Function

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.77

21 January 2018

Voltage-dependent potassium channels in activated rat microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in adipose mass and cellularity through the adult life of rats fed ad libitum or a life-prolonging restricted diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation modulates current amplitude and kinetics of a neuronal voltage-gated potassium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphagia, not hypometabolism, causes early onset obesity in melanocortin-4 receptor knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of human obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory anion currents in Kv1.3 channel-deficient thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nutritional experiments on longevity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Melanocortins and reproduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voluntary exercise delays monogenetic obesity and overcomes reproductive dysfunction of the melanocortin-4 receptor knockout mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermittent administration of brain-derived neurotrophic factor ameliorates glucose metabolism in obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18542083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/IJO.2008.77

1 reference

Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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