(Q24644885)

English

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18704195%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice (English)

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12 January 2020

1

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12 January 2020

5

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12 January 2020

author name string

Zhongjian Zhang

2

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12 January 2020

Chinmoy Sarkar

3

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12 January 2020

Pei-Chih Tsai

4

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12 January 2020

Louis Dye

6

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12 January 2020

Anil B Mukherjee

7

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12 January 2020

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1 September 2008

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12 January 2020

Journal of Clinical Investigation

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12 January 2020

118

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12 January 2020

9

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12 January 2020

3075-3086

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Europe PubMed Central

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12 January 2020

The synaptic vesicle cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation

1 reference

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7 April 2017

Palmitoyl protein thioesterase 1 is targeted to the axons in neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice

1 reference

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7 April 2017

Palmitoyl protein thioesterase (PPT) localizes into synaptosomes and synaptic vesicles in neurons: implications for infantile neuronal ceroid lipofuscinosis (INCL)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Mutations in the palmitoyl protein thioesterase gene causing infantile neuronal ceroid lipofuscinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

SNAP receptors implicated in vesicle targeting and fusion

1 reference

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7 April 2017

SNAREpins: minimal machinery for membrane fusion

1 reference

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7 April 2017

Palmitoylation: policing protein stability and traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Molecular anatomy of a trafficking organelle

1 reference

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7 April 2017

Vesicular proteins exocytosed and subsequently retrieved by compensatory endocytosis are nonidentical

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

An acylation cycle regulates localization and activity of palmitoylated Ras isoforms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Identification of PSD-95 palmitoylating enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Palmitoylation of intracellular signaling proteins: regulation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Evidence for early endosome-like fusion of recently endocytosed synaptic vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Progressively reduced synaptic vesicle pool size in cultured neurons derived from neuronal ceroid lipofuscinosis-1 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Molecular cloning and expression of palmitoyl-protein thioesterase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

Purification and properties of a palmitoyl-protein thioesterase that cleaves palmitate from H-Ras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

7 April 2017

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Genetic modifiers of Drosophila palmitoyl-protein thioesterase 1-induced degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Palmitoylation of ligands, receptors, and intracellular signaling molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Neuronal ceroid lipofuscinoses therapeutic strategies: past, present and future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Molecular mechanisms in membrane traffic at the neuronal synapse: role of protein-lipid interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

The neuronal ceroid-lipofuscinoses: from past to present

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

A pre-synaptic to-do list for coupling exocytosis to endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

The synaptic vesicle: cycle of exocytosis and endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

SNARE complexes prepare for membrane fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Synaptic dysfunction in Huntington's disease: a new perspective.

1 reference

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27 September 2017

Tracking SNARE complex formation in live endocrine cells

1 reference

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27 September 2017

Similarities in Mechanisms and Treatments for Epileptic and Nonepileptic Myoclonus.

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27 September 2017

The genetic spectrum of human neuronal ceroid-lipofuscinoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Current state of clinical and morphological features in human NCL.

1 reference

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27 September 2017

SNARE Protein Structure and Function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Huntington's disease: a synaptopathy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Cell biology of the presynaptic terminal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Palmitoylation sites and processing of synaptotagmin I, the putative calcium sensor for neurosecretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Dynamin and its role in membrane fission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Neurotransmitter secretion along growing nerve processes: comparison with synaptic vesicle exocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

SNAP-25 palmitoylation and plasma membrane targeting require a functional secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Imaging exocytosis and endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

27 September 2017

Synaptic vesicles and exocytosis

1 reference

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27 September 2017

Short-term synaptic plasticity is altered in mice lacking synapsin I.

1 reference

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27 September 2017

Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain

1 reference

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27 September 2017

Synaptic vesicle dynamics in living cultured hippocampal neurons visualized with CY3-conjugated antibodies directed against the lumenal domain of synaptotagmin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

30 May 2018

A palmitoylation cycle dynamically regulates partitioning of the GABA-synthesizing enzyme GAD65 between ER-Golgi and post-Golgi membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

The adhesion molecule CHL1 regulates uncoating of clathrin-coated synaptic vesicles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

CSS-Palm: palmitoylation site prediction with a clustering and scoring strategy (CSS).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

Synaptobrevin is essential for fast synaptic-vesicle endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

Presynaptic trafficking of synaptotagmin I is regulated by protein palmitoylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

Regional and cellular neuropathology in the palmitoyl protein thioesterase-1 null mutant mouse model of infantile neuronal ceroid lipofuscinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

A transient N-terminal interaction of SNAP-25 and syntaxin nucleates SNARE assembly

1 reference

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28 November 2018

Endophilin Is Required for Synaptic Vesicle Endocytosis by Localizing Synaptojanin

1 reference

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28 November 2018

Synaptic strength regulated by palmitate cycling on PSD-95.

1 reference

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28 November 2018

Long-term culture of mouse cortical neurons as a model for neuronal development, aging, and death

1 reference

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28 November 2018

Synaptobrevin 2 is palmitoylated in synaptic vesicles prepared from adult, but not from embryonic brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2515381

28 November 2018

Distinct pools of synaptic vesicles in neurotransmitter release

1 reference

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28 November 2018

N- to C-Terminal SNARE Complex Assembly Promotes Rapid Membrane Fusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18704195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of palmitoyl protein thioesterase in neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/18704195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic vesicles interchange their membrane proteins with a large surface reservoir during recycling

1 reference

https://pubmed.ncbi.nlm.nih.gov/18704195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI33482

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18704195%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18704195%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18704195%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

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