(Q24646924)

2

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Iwona Konieczna

3

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Ling Bei

4

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Elizabeth Horvath

5

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Weiqi Huang

6

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Gurveen Saberwal

7

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Elizabeth A Eklund

Journal of Biological Chemistry

8

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language of work or name

English

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publication date

23 January 2009

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published in

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volume

284

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issue

4

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page(s)

2549-67

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cites work

Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein

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Overexpression of HOXA10 in murine hematopoietic cells perturbs both myeloid and lymphoid differentiation and leads to acute myeloid leukemia

7 April 2017

1 reference

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Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells

7 April 2017

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Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia

7 April 2017

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The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1

7 April 2017

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SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells

7 April 2017

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Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma -induced differentiation of myeloid leukemia cell lines

7 April 2017

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Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells

7 April 2017

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Stage- and lineage-specific expression of the HOXA10 homeobox gene in normal and leukemic hematopoietic cells

7 April 2017

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An Mll-dependent Hox program drives hematopoietic progenitor expansion

7 April 2017

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Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease.

7 April 2017

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The pathophysiology of HOX genes and their role in cancer.

27 September 2017

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Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.

27 September 2017

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Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia

27 September 2017

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Overexpression of the myeloid leukemia-associated Hoxa9 gene in bone marrow cells induces stem cell expansion

27 September 2017

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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

27 September 2017

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HoxA9-mediated immortalization of myeloid progenitors requires functional interactions with TALE cofactors Pbx and Meis

27 September 2017

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Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b

27 September 2017

1 reference

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Isolation and characterization of the cDNA for mouse neutrophil collagenase: demonstration of shared negative regulatory pathways for neutrophil secondary granule protein gene expression

27 September 2017

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CCAAT displacement protein (CDP/cut) recognizes a silencer element within the lactoferrin gene promoter.

27 September 2017

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Constitutive activation of SHP2 in mice cooperates with ICSBP deficiency to accelerate progression to acute myeloid leukemia

27 September 2017

1 reference

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Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.

30 May 2018

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Proliferation of primitive myeloid progenitors can be reversibly induced by HOXA10.

21 January 2018

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HoxA10 represses transcription of the gene encoding p67phox in phagocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804704200

Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis

21 January 2018

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Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

21 January 2018

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Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

21 January 2018

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Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia

21 January 2018

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Activation of SHP2 protein-tyrosine phosphatase increases HoxA10-induced repression of the genes encoding gp91(PHOX) and p67(PHOX)

21 January 2018

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12 December 2020

HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells

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12 December 2020

Quantitative HOX expression in chromosomally defined subsets of acute myelogenous leukemia

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12 December 2020

Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia

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12 December 2020

Characterization of a human macrophage-like cell line stimulated in vitro: a model of macrophage functions

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12 December 2020

Mutations of the PTPN11 gene in therapy-related MDS and AML with rare balanced chromosome translocations

1 reference

12 December 2020