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26 March 2024

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Jacqueline Arp

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Joaquín Madrenas

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Mark G. Kirchhof

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Miren L. Baroja

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26 March 2024

Steven H. Nazarian

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Thu A. Chau

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26 March 2024

Craig A. Strathdee

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Eric H. Ball

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full work available at URL

26 March 2024

language of work or name

English

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publication date

November 2003

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https://mcb.asm.org/content/23/22/8042.full.pdf

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Portable Document Format

online access status

open access

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585965

https://europepmc.org/articles/PMC262363

26 March 2024

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585965

https://europepmc.org/articles/PMC262363?pdf=render

26 March 2024

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open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14585965

https://doi.org/10.1128/mcb.23.22.8042-8057.2003

26 March 2024

online access status

open access

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https://journals.asm.org/doi/pdf/10.1128/MCB.23.22.8042-8057.2003

26 March 2024

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Crossref

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https://www.tandfonline.com/doi/pdf/10.1128/MCB.23.22.8042-8057.2003

26 March 2024

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Crossref

https://api.crossref.org/works/10.1128/MCB.23.22.8042-8057.2003

Molecular and Cellular Biology

26 March 2024

published in

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volume

23

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issue

22

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page(s)

8042-57

0 references

cites work

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ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

7 April 2017

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Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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7 April 2017

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Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum

7 April 2017

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PDE4 inhibitors activate a mitochondrial apoptotic pathway in chronic lymphocytic leukemia cells that is regulated by protein phosphatase 2A.

7 April 2017

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28 September 2017

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28 September 2017

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Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation

28 September 2017

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Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70.

28 September 2017

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Floating the raft hypothesis: lipid rafts play a role in immune cell activation

28 September 2017

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Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor

28 September 2017

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Cyclic nucleotide phosphodiesterases: relating structure and function

28 September 2017

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28 September 2017

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Cytoskeletal polarization and redistribution of cell-surface molecules during T cell antigen recognition

28 September 2017

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28 September 2017

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Therapeutic potential of phosphodiesterase-4 and -3 inhibitors in Th1-mediated autoimmune diseases

28 September 2017

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Cyclic nucleotide phosphodiesterases (PDEs): diverse regulators of cyclic nucleotide signals and inviting molecular targets for novel therapeutic agents

28 September 2017

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28 September 2017

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Efficient control of tetracycline-responsive gene expression from an autoregulated bi-directional expression vector

28 September 2017

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Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor

28 September 2017

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28 September 2017

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Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2

28 September 2017

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Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum

28 September 2017

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Mobility of the human T lymphocyte surface molecules CD3, CD4, and CD8: regulation by a cAMP-dependent pathway

28 September 2017

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Cyclic adenosine 3':5'-monophosphate phosphodiesterase. Distinct forms in human lymphocytes and monocytes

28 September 2017

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Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family

28 September 2017

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Inhibition of PDE4 phosphodiesterase activity induces growth suppression, apoptosis, glucocorticoid sensitivity, p53, and p21(WAF1/CIP1) proteins in human acute lymphoblastic leukemia cells

28 September 2017

1 reference

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The multienzyme PDE4 cyclic adenosine monophosphate-specific phosphodiesterase family: intracellular targeting, regulation, and selective inhibition by compounds exerting anti-inflammatory and antidepressant actions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Antibody binding to CD5 (Tp67) and Tp44 T cell surface molecules: effects on cyclic nucleotides, cytoplasmic free calcium, and cAMP-mediated suppression

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Multiple high-affinity cAMP-phosphodiesterases in human T-lymphocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Inhibition of CD3-linked phospholipase C by phorbol ester and by cAMP is associated with decreased phosphotyrosine and increased phosphoserine contents of PLC-gamma 1

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Inhibition of antigen-specific T cell proliferation and cytokine production by protein kinase A type I.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Clustering of a lipid-raft associated pool of ERM proteins at the immunological synapse upon T cell receptor or CD28 ligation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes

28 November 2018

1 reference

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PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Infection of CD4+ memory T cells by HIV-1 requires expression of phosphodiesterase 4.

28 November 2018

1 reference

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UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Upregulation of cAMP-specific PDE-4 activity following ligation of the TCR complex on thymocytes is blocked by selective inhibitors of protein kinase C and tyrosyl kinases

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=262363

Functions of the N-terminal region of cyclic nucleotide phosphodiesterase 3 (PDE 3) isoforms

28 November 2018

1 reference

12 December 2020

Phosphodiesterases: the journey towards therapeutics

1 reference

12 December 2020

The membrane-microfilament linker ezrin is involved in the formation of the immunological synapse and in T cell activation

1 reference

12 December 2020

Cyclic nucleotide phosphodiesterases from purified human CD4+ and CD8+ T lymphocytes

1 reference

12 December 2020

Cyclic nucleotide phosphodiesterases: gene complexity, regulation by phosphorylation, and physiological implications

1 reference

12 December 2020

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

12 December 2020

CD3- and CD28-dependent induction of PDE7 required for T cell activation

1 reference

12 December 2020

Specific CD3 epsilon association of a phosphodiesterase 4B isoform determines its selective tyrosine phosphorylation after CD3 ligation

1 reference

12 December 2020

The involvement of cAMP in lymphocyte capping

1 reference

12 December 2020

Identifiers

1 reference

957682

957682

1 reference

1 reference

1 reference