(Q24650111)

British Journal of Clinical Pharmacology

ChEBI release 2020-05-28

H K R Thanacoody

1

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language of work or name

English

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publication date

November 2007

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published in

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volume

64

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issue

5

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page(s)

566-74

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cites work

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Methylene blue for malaria in Africa: results from a dose-finding study in combination with chloroquine

7 April 2017

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Inhibitors of type II NADH:menaquinone oxidoreductase represent a class of antitubercular drugs

7 April 2017

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The price of innovation: new estimates of drug development costs

7 April 2017

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Antitubercular activity of trifluoperazine, a calmodulin antagonist

7 April 2017

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Chlorpromazine: A Drug Potentially Useful for Treating Mycobacterial Infections

7 April 2017

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Reversal of resistance in microorganisms by help of non-antibiotics

7 April 2017

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In vitro and ex vivo activity of thioridazine derivatives against Mycobacterium tuberculosis

28 September 2017

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Risk of extrapyramidal syndrome in schizophrenic patients treated with antipsychotics: a population-based study

28 September 2017

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hERG K+ channel blockade by the antipsychotic drug thioridazine: An obligatory role for the S6 helix residue F656.

28 September 2017

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Trypanosoma cruzi dihydrolipoamide dehydrogenase as target for phenothiazine cationic radicals. Effect of antioxidants

28 September 2017

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Searching for new antimalarial therapeutics amongst known drugs

28 September 2017

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"Non-Antibiotics": alternative therapy for the management of MDRTB and MRSA in economically disadvantaged countries.

28 September 2017

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Thioridazine reduces resistance of methicillin-resistant staphylococcus aureus by inhibiting a reserpine-sensitive efflux pump.

28 September 2017

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Molecular determinants of HERG channel block.

28 September 2017

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Characterization of human cytochrome p450 enzymes involved in the metabolism of the piperidine-type phenothiazine neuroleptic thioridazine

28 September 2017

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The in vitro activity of phenothiazines against Mycobacterium avium: potential of thioridazine for therapy of the co-infected AIDS patient.

28 September 2017

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Clinical concentrations of thioridazine enhance the killing of intracellular methicillin-resistant Staphylococcus aureus: an in vivo, ex vivo and electron microscopy study.

28 September 2017

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Mesoridazine: an open-channel blocker of human ether-a-go-go-related gene K+ channel

28 September 2017

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Since phenothiazines alter antibiotic susceptibility of microorganisms by inhibiting efflux pumps, are these agents useful for evaluating similar pumps in phenothiazine-sensitive parasites?

28 September 2017

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Phenothiazines alter resistance of methicillin-resistant strains of Staphylococcus aureus (MRSA) to oxacillin in vitro

28 September 2017

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Trypanosoma cruzi trypanothione reductase inhibitors: phenothiazines and related compounds modify experimental Chagas' disease evolution

28 September 2017

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Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis

28 September 2017

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Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus

28 September 2017

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Intracellular activity of clinical concentrations of phenothiazines including thioridiazine against phagocytosed Staphylococcus aureus

28 September 2017

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Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries

28 September 2017

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Antipsychotic drugs: prolonged QTc interval, torsade de pointes, and sudden death

28 September 2017

1 reference

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Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines

28 September 2017

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Comparative in vitro activity of phenothiazines against multidrug-resistant Mycobacterium tuberculosis

28 September 2017

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Drugs, QT interval abnormalities and ventricular arrhythmias.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Antileishmanial activity of chlorpromazine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Active metabolites of neuroleptic drugs: possible contribution to therapeutic and toxic effects

28 September 2017

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Thioridazine toxicity--an experimental cardiovascular study of thioridazine and its major metabolites in overdose

28 September 2017

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In vitro activities of chloroquine in combination with chlorpromazine or prochlorperazine against isolates of Plasmodium falciparum

28 September 2017

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THIORIDAZINE HYDROCHLORIDE (MELLARIL): ITS EFFECT ON THE ELECTROCARDIOGRAM AND A REPORT OF TWO FATALITIES WITH ELECTROCARDIOGRAPHIC ABNORMALITIES

28 September 2017

1 reference

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Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Trifluoperazine inhibits the incorporation of labelled precursors into lipids, proteins and DNA of Mycobacterium tuberculosis H37Rv.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

The susceptibility of Plasmodium falciparum in vitro to chlorpromazine and the stereo-isomeric compounds cis(Z)- and trans(E)-clopenthixol

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Comparative antidopaminergic properties of thioridazine, mesoridazine and sulforidazine on the corpus striatum

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

A randomized evaluation of the effects of six antipsychotic agents on QTc, in the absence and presence of metabolic inhibition

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Antipsychotics and the risk of sudden cardiac death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Thioridazine and sudden unexplained death in psychiatric in-patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

The in-vitro antimicrobial effect of non-antibiotics and putative inhibitors of efflux pumps on Pseudomonas aeruginosa and Staphylococcus aureus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Photobactericidal activity of methylene blue derivatives against vancomycin-resistant Enterococcus spp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

In vitro activity of phenothiazine derivatives in Enterococcus faecalis and Enterococcus faecium

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Trypanosoma cruzi trypanothione reductase is inactivated by peroxidase-generated phenothiazine cationic radicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Phenothiazine radicals inactivate Trypanosoma cruzi dihydrolipoamide dehydrogenase: enzyme protection by radical scavengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Thioridazine treatment modifies the evolution of Trypanosoma cruzi infection in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Thioridazine treatment prevents cardiopathy in Trypanosoma cruzi infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.03021.X

Treatment with benznidazole or thioridazine in the chronic phase of experimental Chagas disease improves cardiopathy

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Effects of thioridazine and its metabolites on dopaminergic function: drug metabolism as a determinant of the antidopaminergic actions of thioridazine.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2203271

Thioridazine and EKG anomalies

28 November 2018

1 reference

12 December 2020

Lethal Effect of Phenothiazine Neuroleptics on the Pathogenic ProtozoanLeishmania donovani

1 reference

12 December 2020

Thioridazine-5-sulfoxide cardiotoxicity in the isolated, perfused rat heart

1 reference

12 December 2020

Thioridazine 5-sulfoxide diastereoisomers in serum and urine from rats and man after chronic thioridazine administration

1 reference

12 December 2020

Receptor affinity, neurochemistry and behavioral characteristics of the enantiomers of thioridazine: evidence for different stereoselectivities at D1 and D2 receptors in rat brain

1 reference

12 December 2020

Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype

1 reference

12 December 2020

A survey of sudden death associated with the use of antipsychotic or antidepressant drugs: 49 cases in Finland

1 reference

12 December 2020

Calmodulin-like activity in mycobacteria

1 reference

12 December 2020

Correlation between calmodulin-like protein, phospholipids, and growth inglucose-grown Mycobacterium phlei

1 reference

12 December 2020

Comparison of the effects of thioridazine and mesoridazine on the QT interval in healthy adults after single oral doses.

1 reference

12 December 2020

Factors Affecting Drug Concentrations and QT Interval During Thioridazine Therapy

1 reference

12 December 2020

In vitro activities of phenothiazine-type calmodulin antagonists against Mycobacterium leprae

1 reference

12 December 2020

QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients

1 reference

12 December 2020

The heart of psychotropic drug therapy

1 reference

12 December 2020

Concentration-related pharmacodynamic effects of thioridazine and its metabolites in humans

1 reference

12 December 2020

Effect of trifluoperazine on in vitro ATP synthesis by Mycobacterium leprae

1 reference

12 December 2020

Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current

1 reference

12 December 2020

Clinical, biochemical and post mortem studies on a patient treated with chlorpromazine

1 reference

12 December 2020