(Q24669674)

1

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M Hornig

2

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C Pergola

3

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N Meindl

4

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L Franke

5

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Y Tanrikulu

6

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G Dodt

7

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G Schneider

8

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D Steinhilber

9

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O Werz

British Journal of Pharmacology

10

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language of work or name

English

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publication date

October 2007

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published in

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volume

152

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issue

4

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page(s)

471-80

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cites work

5-Lipoxygenase interacts with coactosin-like protein

1 reference

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5-lipoxygenase-activating protein is an arachidonate binding protein

7 April 2017

1 reference

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Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

7 April 2017

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Prostaglandins and leukotrienes: advances in eicosanoid biology

7 April 2017

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Capacity for repeatable leukotriene generation after transient stimulation of mast cells and macrophages

7 April 2017

1 reference

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Role of the 5-lipoxygenase-activating protein (FLAP) in murine acute inflammatory responses

7 April 2017

1 reference

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Rapid import of cytosolic 5-lipoxygenase into the nucleus of neutrophils after in vivo recruitment and in vitro adherence

7 April 2017

1 reference

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Development of 5-lipoxygenase inhibitors--lessons from cellular enzyme regulation

7 April 2017

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Fuzzy pharmacophore models from molecular alignments for correlation-vector-based virtual screening

28 September 2017

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5-Lipoxygenase: Cellular Biology and Molecular Pharmacology

28 September 2017

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28 September 2017

Licofelone (Merckle).

1 reference

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Anti-inflammatory drugs: new multitarget compounds to face an old problem. The dual inhibition concept.

28 September 2017

1 reference

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Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes

28 September 2017

1 reference

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A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6.

28 September 2017

1 reference

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Sequential induction of 5-lipoxygenase gene expression and activity in Mono Mac 6 cells by transforming growth factor beta and 1,25-dihydroxyvitamin D3

28 September 2017

1 reference

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The mechanism of action of the new antiinflammatory compound ML3000: inhibition of 5-LOX and COX-1/2.

28 September 2017

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5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase

30 May 2018

1 reference

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Serum factors regulate 5-lipoxygenase activity in maturating HL60 cells

30 May 2018

1 reference

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Pharmacological profile of a new pyrrolizine derivative inhibiting the enzymes cyclo-oxygenase and 5-lipoxygenase

30 May 2018

1 reference

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Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivo

30 May 2018

1 reference

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L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

30 May 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

30 May 2018

12 December 2020

Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-yl-methoxy)- indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610.

30 May 2018

1 reference

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Phosphorylation- and stimulus-dependent inhibition of cellular 5-lipoxygenase activity by nonredox-type inhibitors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Licofelone, a dual lipoxygenase-cyclooxygenase inhibitor, downregulates polymorphonuclear leukocyte and platelet function

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Nonredox 5-lipoxygenase inhibitors require glutathione peroxidase for efficient inhibition of 5-lipoxygenase activity

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2050828

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes

28 November 2018

1 reference

12 December 2020

Identification and isolation of a membrane protein necessary for leukotriene production

1 reference

12 December 2020

5-Lipoxygenase-activating protein is the target of a quinoline class of leukotriene synthesis inhibitors

1 reference

12 December 2020

In vitro pharmacology of BAY X1005, a new inhibitor of leukotriene synthesis

1 reference

12 December 2020

(6,7-Diaryldihydropyrrolizin-5-yl)acetic acids, a novel class of potent dual inhibitors of both cyclooxygenase and 5-lipoxygenase

1 reference

12 December 2020

Characterization of 5-lipoxygenase inhibitors in biochemical and functional in vivo assays

1 reference

12 December 2020

Selenium-dependent peroxidases suppress 5-lipoxygenase activity in B-lymphocytes and immature myeloid cells. The presence of peroxidase-insensitive 5-lipoxygenase activity in differentiated myeloid cells

1 reference

12 December 2020